Vitiligo is an autoimmune depigment disease results from extensive melanocytes
destruction. The destruction of melanocyte is thought to be of multifactorial causation …

Aneuploidy has been recognized as a hallmark of tumorigenesis for more than 100 years,
but the connection between chromosomal errors and malignant growth has remained …

Vitiligo is a common chronic acquired pigmentation disorder characterized by loss of
pigmentation. Among various hypotheses proposed for the pathogenesis of vitiligo, oxidative …

From a holistic point of view, aging results from the cumulative erosion of the various
systems. Among these, the immune system is interconnected to the rest as immune cells are …

Astroglia represent a class of heterogeneous, in form and function, cells known as
astrocytes, which provide for homoeostasis and defence of the central nervous system …

The therapeutic induction of senescence is a potential means to treat cancer, primarily
acting through the induction of a persistent growth‐arrested state in tumors. However, recent …

The tumor microenvironment (TME) is a complex environment where cancer cells reside and
interact with different types of cells, secreted factors, and the extracellular matrix …

Background Glioblastoma is one of the most devastating and incurable cancers due to its
aggressive behaviour and lack of available therapies, being its overall-survival from …

Senotherapy, a promising therapeutic strategy, has drawn a lot attention recently due to its
potential for combating cancer. Senotherapy refers to the targeting of senescent cells to …

Dry age-related macular degeneration (AMD) is marked by the accumulation of extracellular
and intracellular lipid-rich deposits within and around the retinal pigment epithelium (RPE) …