The present review paper focuses on the chemistry of oxidative stress mitigation by
antioxidants. Oxidative stress is understood as a lack of balance between the pro-oxidant …

The study of the intestinal or gut microbiome is a newer field that is rapidly gaining attention.
Bidirectional communication between gut microbes and the host can impact numerous …

Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

Parkinson's disease (PD) is a neurodegenerative disorder which mainly targets motor
symptoms such as tremor, rigidity, bradykinesia and postural instability. The physiological …

Parkinson's disease (PD) is a growing burden worldwide, and there is no reliable biomarker
used in clinical routines to date. Cerebrospinal fluid (CSF) is routinely collected in patients …

Oxidative stress has been suggested to play a key role in Parkinson's disease, but
inconsistent results were found in clinical studies. This study sought to quantitatively …

Parkinson's disease (PD) is the second most common neurodegenerative disorder of the
elderly, presenting primarily with symptoms of motor impairment. The disease is diagnosed …

Objective Mitochondrial dysfunction, oxidative stress and chondrocyte death are important
contributors to the development and pathogenesis of osteoarthritis (OA). In this study, we …

Brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-related kinase
receptor type B (TrkB) are widely distributed in multiple regions of the human brain …

As the leading causes of human disability and mortality, neurological diseases affect
millions of people worldwide and are on the rise. Although the general roles of several …