Thermal immuno-nanomedicine in cancer

Z Yang, D Gao, J Zhao, G Yang, M Guo… - Nature Reviews …, 2023 - nature.com
Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …

Next generation gold drugs and probes: chemistry and biomedical applications

RT Mertens, S Gukathasan, AS Arojojoye… - Chemical …, 2023 - ACS Publications
The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

Synergistic reinforcing of immunogenic cell death and transforming tumor‐associated macrophages via a multifunctional cascade bioreactor for optimizing cancer …

C Huang, B Lin, C Chen, H Wang, X Lin… - Advanced …, 2022 - Wiley Online Library
Immunogenic cell death (ICD) has aroused widespread attention because it can reconstruct
a tumor microenvironment and activate antitumor immunity. This study proposes a two‐way …

Sono‐controllable and ROS‐sensitive CRISPR‐Cas9 genome editing for augmented/synergistic ultrasound tumor nanotherapy

Y Pu, H Yin, C Dong, H Xiang, W Wu, B Zhou… - Advanced …, 2021 - Wiley Online Library
The potential of the cluster regularly interspaced short palindromic repeat (CRISPR)‐
associated protein 9 (Cas9)‐based therapeutic genome editing is severely hampered by the …

A Microenvironment Dual‐Responsive Nano‐Drug Equipped with PD‐L1 Blocking Peptide Triggers Immunogenic Pyroptosis for Prostate Cancer Self‐Synergistic …

H Wang, Z Gao, D Jiao, Y Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Induction of immunogenic cell death (ICD) in tumor combined with immune checkpoint
blockade (ICB) therapy is widely developed to improve the efficacy of cancer …

Walking dead tumor cells for targeted drug delivery against lung metastasis of triple‐negative breast cancer

Z Zhao, L Fang, P Xiao, X Sun, L Zhou, X Liu… - Advanced …, 2022 - Wiley Online Library
Lung metastasis is challenging in patients with triple‐negative breast cancer (TNBC).
Surgery is always not available due to the dissemination of metastatic foci and most drugs …

Nanoparticle‐Based Photothermal Therapy for Breast Cancer Noninvasive Treatment

Y Xiong, Y Rao, J Hu, Z Luo, C Chen - Advanced materials, 2023 - Wiley Online Library
Rapid advancements in materials science and nanotechnology, intertwined with oncology,
have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy …

Sonosensitized aggregation-induced emission dots with capacities of immunogenic cell death induction and multivalent blocking of programmed cell death-ligand 1 …

S Jia, Z Gao, Z Wu, H Gao, H Wang, H Ou… - CCS …, 2022 - chinesechemsoc.org
The combination of immunogenic cell death (ICD) induction and immune checkpoint
blockade has emerged as a major direction of cancer immunotherapy. Among currently …

A STING pathway-activatable contrast agent for MRI-guided tumor immunoferroptosis synergistic therapy

S Guo, W Xiong, J Zhu, J Feng, R Zhou, Q Fan… - Biomaterials, 2023 - Elsevier
The immunotherapy efficiency of stimulator of interferon genes (STING)-activatable drugs
(eg, 7-ethyl-10-hydroxycamptothecin, SN38) is limited by their non-specificity to tumor cells …

Glutathione‐depleting organic metal adjuvants for effective NIR‐II photothermal immunotherapy

Y Chen, P He, D Jana, D Wang, M Wang… - Advanced …, 2022 - Wiley Online Library
Although photothermal immunotherapy (PTI) is a compelling strategy for tumor therapy, the
development of promising photothermal agents to overcome the insufficient immunogenicity …