In the past century, few areas of biology advanced as much as our understanding of the
pathways of intermediary metabolism. Initially considered unimportant in terms of gene …

Proteins regulate gene expression by controlling mRNA biogenesis, localization, translation
and decay. Identifying the composition, diversity and function of mRNA–protein complexes …

RNA-binding proteins play a key role in the regulation of all aspects of RNA metabolism,
from the synthesis of RNA to its decay. Protein-RNA interactions have been thought to be …

Transcriptome-wide identification of RNA-binding proteins (RBPs) is a prerequisite for
understanding the posttranscriptional gene regulation networks. However, proteomic …

Background RNA-binding proteins (RBPs) play important roles in cellular homeostasis by
controlling gene expression at the post-transcriptional level. Results We explore the …

RNA-protein interactions drive fundamental biological processes and are targets for
molecular engineering, yet quantitative and comprehensive understanding of the sequence …

RNA-binding proteins (RBPs) control all aspects of RNA fate, and defects in their function
underlie a broad spectrum of human pathologies. We focus here on two recent studies that …

RNA metabolism is controlled by an expanding, yet incomplete, catalog of RNA-binding
proteins (RBPs), many of which lack characterized RNA binding domains. Approaches to …

RNA-binding proteins (RBPs) are essential for post-transcriptional regulation of gene
expression. Recent high-throughput screens have dramatically increased the number of …

Owing to their preeminent biological functions, the repertoire of expressed RNA-binding
proteins (RBPs) and their activity states are highly informative about cellular systems. We …