RNA binding proteins as pioneer determinants of infection: protective, proviral, or both?
As the first intracellular host factors that directly interact with the genomes of RNA viruses,
RNA binding proteins (RBPs) have a profound impact on the outcome of an infection …
RNA binding proteins (RBPs) have a profound impact on the outcome of an infection …
Multifunctional roles for the protein translocation machinery in RNA anchoring to the endoplasmic reticulum
Signal sequence-encoding mRNAs undergo translation-dependent localization to the
endoplasmic reticulum (ER) and at the ER are anchored via translation on Sec61-bound …
endoplasmic reticulum (ER) and at the ER are anchored via translation on Sec61-bound …
In silico characterization and prediction of global protein–mRNA interactions in yeast
V Pancaldi, J Bähler - Nucleic acids research, 2011 - academic.oup.com
Post-transcriptional gene regulation is mediated through complex networks of protein–RNA
interactions. The targets of only a few RNA binding proteins (RBPs) are known, even in the …
interactions. The targets of only a few RNA binding proteins (RBPs) are known, even in the …
[HTML][HTML] RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma
Medulloblastoma, the most common malignant brain tumor in children, is a disease whose
mechanisms are now beginning to be uncovered by high-throughput studies of somatic …
mechanisms are now beginning to be uncovered by high-throughput studies of somatic …
The expanding world of metabolic enzymes moonlighting as RNA binding proteins
NJ Curtis, CJ Jeffery - Biochemical Society Transactions, 2021 - portlandpress.com
RNA binding proteins play key roles in many aspects of RNA metabolism and function,
including splicing, transport, translation, localization, stability and degradation. Within the …
including splicing, transport, translation, localization, stability and degradation. Within the …
Insight into novel RNA-binding activities via large-scale analysis of lncRNA-bound proteome and IDH1-bound transcriptome
RNA-binding proteins (RBPs) play pivotal roles in directing RNA fate and function. Yet the
current annotation of RBPs is largely limited to proteins carrying known RNA-binding …
current annotation of RBPs is largely limited to proteins carrying known RNA-binding …
Highly accurate and high-resolution function prediction of RNA binding proteins by fold recognition and binding affinity prediction
A full understanding of the mechanism of post-transcriptional regulation requires more than
simple two-state prediction (binding or not binding) for RNA binding proteins. Here we report …
simple two-state prediction (binding or not binding) for RNA binding proteins. Here we report …
An essential role for COPI in mRNA localization to mitochondria and mitochondrial function
D Zabezhinsky, B Slobodin, D Rapaport, JE Gerst - Cell reports, 2016 - cell.com
Nuclear-encoded mRNAs encoding mitochondrial proteins (mMPs) can localize directly to
the mitochondrial surface, yet how mMPs target mitochondria and whether RNA targeting …
the mitochondrial surface, yet how mMPs target mitochondria and whether RNA targeting …
Life and work of stress granules and processing bodies: new insights into their formation and function
M Perez-Pepe, AJ Fernández-Alvarez… - Biochemistry, 2018 - ACS Publications
The dynamic formation of stress granules (SGs), processing bodies (PBs), and related RNA
organelles regulates diverse cellular processes, including the coordination of functionally …
organelles regulates diverse cellular processes, including the coordination of functionally …
Quantitative proteomic analysis reveals concurrent RNA–protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae
A growing body of evidence supports the existence of an extensive network of RNA-binding
proteins (RBPs) whose combinatorial binding affects the post-transcriptional fate of every …
proteins (RBPs) whose combinatorial binding affects the post-transcriptional fate of every …