The implementation of innovative approaches is crucial in an ongoing endeavor to mitigate
the impact of COVID-19 pandemic. The present study examines the strategic application of …

Herein we report for the first time an efficient synthetic procedure for the preparation of N-aryl-
N'-ureido-O-sulfamates (AUSs) as a new class of Carbonic Anhydrase Inhibitors (CAIs). The …

Two pathways toward 6-selanyl-2-triazolylpurine derivatives were designed. The first
method involved the synthesis of 2-chloro-6-selanylpurine derivatives, further SNAr reaction …

Carbonic anhydrase (CA) is a zinc-dependent metal enzyme that maintains the pH and
carbon dioxide (CO 2) homeostasis in cells by catalyzing the reversible hydration and …

A novel series of thio-and seleno-acetamides bearing benzenesulfonamide were
synthetized and tested as human carbonic anhydrase inhibitors. These compounds were …

Symmetrical ditocopheryl disulfides (Toc) 2S2 and symmetrical and unsymmetrical
ditocopheryl sulfides (Toc) 2S were simply prepared under remarkably mild conditions with …

A series of benzoselenoates has been prepared and their inhibitory properties against the
most relevant human Carbonic Anhydrases (CAs) isoforms, among which hCA I, II, IV, VII, IX …

Developing novel functional polyhedral oligomeric silsesquioxane (POSS) for various
applications is highly desirable. Herein we present the first example of a novel selenone …

We present a facile, visible-light-driven, selenyl-radical-mediated, cascade spirocyclization
of 3-(2-isocyanobenzyl) indoles with diselenides that affords various selenylated spiro …

A new methodology for the synthesis of small molecules containing the S-Se bond is
reported. Aryl-and alkyl-selenols react smoothly with N-thiophthalimides to afford the …