Disorders of cell number that result from an imbalance between the death of parenchymal
cells and the proliferation or recruitment of maladaptive cells contributes to the pathogenesis …

Acute kidney injury (AKI) is a prevalent pathological condition that is characterized by a
precipitous decline in renal function. In recent years, a growing body of studies have …

Acute kidney injury (AKI) exhibits high morbidity and mortality. Kidney injury molecule-1
(KIM1) is dramatically upregulated in renal tubules upon injury, and acts as a biomarker for …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are interconnected conditions,
and CKD is projected to become the fifth leading global cause of death by 2040. New …

Renal fibrosis is a common consequence of various progressive nephropathies, including
obstructive nephropathy, and ultimately leads to kidney failure. Infiltration of inflammatory …

In both humans and mice, repair of acute kidney injury is worse in males than in females.
Here, we provide evidence that this sexual dimorphism results from sex differences in …

Background Kidney insults due to various pathogenic factors, such as trauma, infection, and
inflammation, can cause tubular epithelial cell injury and death, leading to acute kidney …

Chronic kidney disease (CKD) is a major public health concern, underscoring a need to
identify pathogenic mechanisms and potential therapeutic targets. Reactive oxygen species …

Acute kidney injury (AKI) represents a prevailing complication of sepsis, and its onset
involves ferroptosis. Ginsenoside Rg1 exerts a positive effect on kidney diseases. This study …

Sepsis-associated acute kidney injury (SA-AKI) is common in patients with severe sepsis,
and has a high incidence rate and high mortality rate in ICU patients. Most patients progress …