This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …

Osteoarthritis (OA) is one of the most common degenerative joint diseases, significantly
impacting individuals and society. With the acceleration of global aging, the incidence of OA …

Approaches to the design and construction of biomimetic scaffolds for osteochondral tissue,
show increasing advances. Considering the limitations of this tissue in terms of repair and …

Background The disease COVID-19, caused by SARS-CoV-2 infection, has a systemic effect
and is associated with a number of pathophysiological mechanisms that mobilize a wide …

Herein, we evaluated the in vivo effects of meloxicam and curcumin co-encapsulated PLGA
nanoparticles in experimental acute models of pyrexia, nociception, and inflammation …

Abstract Post-traumatic osteoarthritis (PTOA), a disorder of the synovium, subchondral bone,
and cartilage that affects the entire joint, constitutes approximately 12% of all cases of …

Up to 50% of individuals develop post-traumatic osteoarthritis (PTOA) within 10 years
following knee-joint injuries such as anterior cruciate ligament rupture or acute meniscal …

The knee is the joint most frequently involved in osteoarthritis, a common joint disorder in the
adult population that is associated with significant chronic joint pain, reduced mobility and …

MKARE®, a 100% natural ingredient derived from fresh eggshell membrane (ESM), has a
rich composition in bioactive compounds like collagen, hyaluronic acid, and elastin. These …

Background Intervertebral disc degeneration (IVDD) is an essential cause of low back pain
(LBP), the incidence of which has risen in recent years and is progressively younger, but …