[HTML][HTML] Targeting non-coding RNAs to overcome cancer therapy resistance

BQ Chen, MP Dragomir, C Yang, Q Li, D Horst… - Signal transduction and …, 2022 - nature.com
It is now well known that non-coding RNAs (ncRNAs), rather than protein-coding transcripts,
are the preponderant RNA transcripts. NcRNAs, particularly microRNAs (miRNAs), long non …

Blood‐based biomarkers of human papillomavirus–associated cancers: A systematic review and meta‐analysis

S Balachandra, SB Kusin, R Lee, JM Blackwell… - Cancer, 2021 - Wiley Online Library
Background Despite the significant societal burden of human papillomavirus (HPV)–
associated cancers, clinical screening interventions for HPV‐associated noncervical …

[HTML][HTML] CircRNF220, not its linear cognate gene RNF220, regulates cell growth and is associated with relapse in pediatric acute myeloid leukemia

X Liu, X Liu, M Cai, A Luo, Y He, S Liu, X Zhang… - Molecular cancer, 2021 - Springer
Abstract Background Circular RNAs (circRNAs) constitute a family of transcripts with unique
structures and have been confirmed to be critical in tumorigenesis and to be potential …

[HTML][HTML] MicroRNA-106a regulates autophagy-related cell death and EMT by targeting TP53INP1 in lung cancer with bone metastasis

L Han, Z Huang, Y Liu, L Ye, D Li, Z Yao, C Wang… - Cell death & …, 2021 - nature.com
Bone metastasis is one of the most serious complications in lung cancer patients.
MicroRNAs (miRNAs) play important roles in tumour development, progression and …

[HTML][HTML] Long noncoding RNA expression independently predicts outcome in pediatric acute myeloid leukemia

JE Farrar, JL Smith, M Othus, BJ Huang… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
PURPOSE Optimized strategies for risk classification are essential to tailor therapy for
patients with biologically distinctive disease. Risk classification in pediatric acute myeloid …

[HTML][HTML] Identification and validation of a prognostic risk-scoring model based on ferroptosis-associated cluster in acute myeloid leukemia

J Wang, Z Zhuo, Y Wang, S Yang, J Chen… - Frontiers in cell and …, 2022 - frontiersin.org
Background: Emerging evidence has proven that ferroptosis plays an important role in the
development of acute myeloid leukemia (AML), whereas the exact role of ferroptosis …

[HTML][HTML] Exosomal MiRNAs in pediatric cancers

A Galardi, M Colletti, V Di Paolo, P Vitullo… - International Journal of …, 2019 - mdpi.com
MicroRNAs (miRNAs) have generated great attention in oncology as they play a
fundamental role in the regulation of gene expression and their aberrant expression is …

[HTML][HTML] A gut microbiota score predicting acute graft-versus-host disease following myeloablative allogeneic hematopoietic stem cell transplantation

L Han, K Zhao, Y Li, H Han, L Zhou, P Ma, Z Fan… - American Journal of …, 2020 - Elsevier
Although studies have reported that intestinal microbiota are associated with acute graft-
versus-host disease (aGVHD), they lacked a satisfactory method for predicting aGVHD. We …

[HTML][HTML] miRNA-1 promotes acute myeloid leukemia cell pathogenesis through metabolic regulation

A Ghazaryan, JA Wallace, WW Tang, C Barba… - Frontiers in …, 2023 - frontiersin.org
Acute myeloid leukemia (AML) is a heterogeneous and deadly disease characterized by
uncontrolled expansion of malignant blasts. Altered metabolism and dysregulated …

[HTML][HTML] MicroRNA-181a as novel liquid biopsy marker of central nervous system involvement in pediatric acute lymphoblastic leukemia

B Egyed, N Kutszegi, JC Sági, A Gézsi… - Journal of Translational …, 2020 - Springer
Background Refractory central nervous system (CNS) involvement is among the major
causes of therapy failure in childhood acute leukemia. Applying contemporary diagnostic …