[HTML][HTML] Genetics, genomics and emerging molecular therapies of pancreatic cancer

J Liu, M Mroczek, A Mach, M Stępień, A Aplas… - Cancers, 2023 - mdpi.com
Simple Summary This review article is a summary of the current state of knowledge
regarding the genetics of pancreatic cancer and a presentation of possible treatment options …

The role of psychologic stress in cancer initiation: Clinical relevance and potential molecular mechanisms

M Falcinelli, PH Thaker, SK Lutgendorf, SD Conzen… - Cancer research, 2021 - AACR
The hypothesis that the physiologic response to psychologic stress influences the initiation
of cancer is highly controversial. The link between initiating stressors, the psychologic stress …

Young-age prostate cancer

S Hussein, S Satturwar, T Van der Kwast - Journal of clinical pathology, 2015 - jcp.bmj.com
Although prostate cancer is a disease of the elderly, its diagnosis is not uncommonly made
in men younger than 55 years. Both ethnic, familial and genetic factors play a role in the …

[HTML][HTML] BRCA Genes and Related Cancers: A Meta-Analysis from Epidemiological Cohort Studies

YC Lee, YL Lee, CY Li - Medicina, 2021 - mdpi.com
Background and Objectives: BRCA1 and BRCA2 are genes located in different
chromosomes that are disproportionately associated with hereditary breast and ovarian …

[HTML][HTML] Function of PIN1 in cancer development and its inhibitors as cancer therapeutics

JH Yu, CY Im, SH Min - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Peptidyl-prolyl isomerase (PIN1) specifically binds and isomerizes the phosphorylated
serine/threonine–proline (pSer/Thr–Pro) motif, which results in the alteration of protein …

[HTML][HTML] Biological interpretation of deep neural network for phenotype prediction based on gene expression

B Hanczar, F Zehraoui, T Issa, M Arles - BMC bioinformatics, 2020 - Springer
Background The use of predictive gene signatures to assist clinical decision is becoming
more and more important. Deep learning has a huge potential in the prediction of phenotype …

Prostate cancer early detection, version 2.2015

PR Carroll, JK Parsons, G Andriole… - Journal of the National …, 2015 - jnccn.org
Prostate cancer represents a spectrum of disease that ranges from nonaggressive, slow-
growing disease that may not require treatment to aggressive, fast-growing disease that …

Endometrial cancer in germline BRCA mutation carriers: a systematic review and meta-analysis

E Matanes, A Volodarsky-Perel, N Eisenberg… - Journal of Minimally …, 2021 - Elsevier
Objective Risk-reducing salpingo-oophorectomy (RRSO) is standard treatment among
women with BRCA mutations. The aim of this meta-analysis is to evaluate the risk of …

Skin diseases of the breast and nipple: benign and malignant tumors

RA Waldman, J Finch, JM Grant-Kels… - Journal of the American …, 2019 - Elsevier
The evaluation and management of dermatologic diseases of the breast and nipple requires
an understanding of the unique anatomy of the breast and nipple and an awareness of the …

[HTML][HTML] Emerging evidences for an implication of the neurodegeneration-associated protein tau in cancer

S Papin, P Paganetti - Brain sciences, 2020 - mdpi.com
Neurodegenerative disorders and cancer may appear unrelated illnesses. Yet,
epidemiologic studies indicate an inverse correlation between their respective incidences …