Mechanisms of immune regulation in allergic diseases: the role of regulatory T and B cells
O Palomares, M Akdis, M Martín‐Fontecha… - Immunological …, 2017 - Wiley Online Library
Allergy is a major public health problem with a high socio‐economic impact. The number of
allergic patients is expected to reach to four billion within two decades when the World's …
allergic patients is expected to reach to four billion within two decades when the World's …
[HTML][HTML] Toll-like receptor agonists as adjuvants for allergen immunotherapy
ME Kirtland, DC Tsitoura, SR Durham… - Frontiers in …, 2020 - frontiersin.org
Toll-like receptors (TLRs) are essential components of innate immunity and provide
defensive inflammatory responses to invading pathogens. Located within the plasma …
defensive inflammatory responses to invading pathogens. Located within the plasma …
[HTML][HTML] TLR9 and COVID-19: a multidisciplinary theory of a multifaceted therapeutic target
GFG Bezemer, J Garssen - Frontiers in Pharmacology, 2021 - frontiersin.org
By mapping the clinical pathophysiology of the novel coronavirus disease 2019 (COVID-19)
against insights from virology, immunology, genomics, epidemiology and pharmacology, it is …
against insights from virology, immunology, genomics, epidemiology and pharmacology, it is …
DNA and mRNA vaccination against allergies
S Scheiblhofer, J Thalhamer… - Pediatric Allergy and …, 2018 - Wiley Online Library
Allergen‐specific immunotherapy, which is performed by subcutaneous injection or
sublingual application of allergen extracts, represents an effective treatment against type I …
sublingual application of allergen extracts, represents an effective treatment against type I …
[HTML][HTML] CpG adjuvant in allergen-specific immunotherapy: finding the sweet spot for the induction of immune tolerance
G Montamat, C Leonard, A Poli, L Klimek… - Frontiers in …, 2021 - frontiersin.org
Prevalence and incidence of IgE-mediated allergic diseases have increased over the past
years in developed and developing countries. Allergen-specific immunotherapy (AIT) is …
years in developed and developing countries. Allergen-specific immunotherapy (AIT) is …
Dental follicle mesenchymal stem cells down‐regulate Th2‐mediated immune response in asthmatic patients mononuclear cells
D Genç, N Zibandeh, E Nain, M Gökalp… - Clinical & …, 2018 - Wiley Online Library
Background Asthma is a chronic inflammatory disease in which inflammatory responses
have the polarisation of CD 4+ T cells to Th2 cells. Dental follicle mesenchymal stem cells …
have the polarisation of CD 4+ T cells to Th2 cells. Dental follicle mesenchymal stem cells …
Melatonin biosynthesis restored by CpG oligodeoxynucleotides attenuates allergic airway inflammation via regulating NLRP3 inflammasome
HM Wu, QM Xie, CC Zhao, J Xu, XY Fan, GH Fei - Life sciences, 2019 - Elsevier
Abstract Aims Both CpG oligodeoxynucleotide (CpG-ODN) and melatonin have been
reported to induce Th1 response and contribute to allergic asthma resistance. Here, we …
reported to induce Th1 response and contribute to allergic asthma resistance. Here, we …
Toll-like receptor 9–dependent interferon production prevents group 2 innate lymphoid cell–driven airway hyperreactivity
CLP Thio, ACY Lai, PY Chi, G Webster… - Journal of Allergy and …, 2019 - Elsevier
Background Group 2 innate lymphoid cells (ILC2s) are important mediators of allergic
asthma. Bacterial components, such as unmethylated CpG DNA, a Toll-like receptor (TLR) 9 …
asthma. Bacterial components, such as unmethylated CpG DNA, a Toll-like receptor (TLR) 9 …
[HTML][HTML] TLR9–IL-2 axis exacerbates allergic asthma by preventing IL-17A hyperproduction
Y Murakami, T Ishii, H Nunokawa, K Kurata, T Narita… - Scientific Reports, 2020 - nature.com
Allergic asthma is one of most famous allergic diseases, which develops lung and airway
inflammation. Recent studies have revealed the relationship between the pathology of …
inflammation. Recent studies have revealed the relationship between the pathology of …
Interplay of IL-33 and IL-35 Modulates Th2/Th17 Responses in Cigarette Smoke Exposure HDM-Induced Asthma
J Liu, B Su, P Tao, X Yang, L Zheng, Y Lin, X Zou… - Inflammation, 2024 - Springer
Cigarette smoke (CS) facilitates adverse effects on the airway inflammation and treatment of
asthma. Here, we investigated the mechanisms by which CS exacerbates asthma. The roles …
asthma. Here, we investigated the mechanisms by which CS exacerbates asthma. The roles …