[HTML][HTML] Natural killer cells: In health and disease
A Mandal, C Viswanathan - Hematology/oncology and stem cell therapy, 2015 - Elsevier
Natural killer (NK) cells constitute our bodies' frontline defense system, guarding against
tumors and launching attacks against infections. The activities of NK cells are regulated by …
tumors and launching attacks against infections. The activities of NK cells are regulated by …
Role of chemokines in the biology of natural killer cells
MJ Robertson - Journal of leukocyte biology, 2002 - academic.oup.com
Natural killer (NK) cells participate in innate and adaptive immuneresponses to obligate
intracellular pathogens and malignant tumors. Twomajor NK cell subsets have been …
intracellular pathogens and malignant tumors. Twomajor NK cell subsets have been …
Expansion of highly cytotoxic human natural killer cells for cancer cell therapy
H Fujisaki, H Kakuda, N Shimasaki, C Imai, J Ma… - Cancer research, 2009 - AACR
Infusions of natural killer (NK) cells are an emerging tool for cancer immunotherapy. The
development of clinically applicable methods to produce large numbers of fully functional …
development of clinically applicable methods to produce large numbers of fully functional …
Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells
C Imai, S Iwamoto, D Campana - Blood, 2005 - ashpublications.org
Natural killer (NK) cells hold promise for improving the therapeutic potential of allogeneic
hematopoietic transplantation, but their effectiveness is limited by inhibitory HLA types. We …
hematopoietic transplantation, but their effectiveness is limited by inhibitory HLA types. We …
Chimeric receptors with 4-1BB stimulatory signaling domain
D Campana, C Imai - US Patent 8,399,645, 2013 - Google Patents
The present invention relates to a chimeric receptor capable of signaling both a primary and
a co-stimulatory pathway, thus allowing activation of the co-stimulatory pathway with out …
a co-stimulatory pathway, thus allowing activation of the co-stimulatory pathway with out …
Large-scale ex vivo expansion and characterization of natural killer cells for clinical applications
N Lapteva, AG Durett, J Sun, LA Rollins, LL Huye… - …, 2012 - Taylor & Francis
Background aims. Interest in natural killer (NK) cell-based immunotherapy has resurged
since new protocols for the purification and expansion of large numbers of clinical-grade …
since new protocols for the purification and expansion of large numbers of clinical-grade …
CD69 is a stimulatory receptor for natural killer cell and its cytotoxic effect is blocked by CD94 inhibitory receptor
CD69 is a differentiation antigen expressed shortly after activation on T lymphocytes and
other cells of haematopoietic origin, including natural killer (NK) cells. The function of CD69 …
other cells of haematopoietic origin, including natural killer (NK) cells. The function of CD69 …
[HTML][HTML] Generating natural killer cells for adoptive transfer: expanding horizons
Natural killer (NK) cells are unique innate lymphoid cells that have therapeutic potential in
adoptive cell transfer-based cancer immunotherapy that has been established across a …
adoptive cell transfer-based cancer immunotherapy that has been established across a …
Immunomodulatory Properties of Coriolus versicolor: The Role of Polysaccharopeptide
Traditional uses of herbal medicine have depended mostly on anecdotal evidence for much
of history. The increasing application of scientific rigor to the study some of these traditional …
of history. The increasing application of scientific rigor to the study some of these traditional …
Expansion and activation of natural killer cells for cancer immunotherapy
D Cho, D Campana - The Korean journal of laboratory …, 2009 - synapse.koreamed.org
Natural killer (NK) cells can kill a wide range of cancer cells and are a promising tool for cell
therapy of cancer. NK cells cytotoxicity is regulated by a balance between stimulatory and …
therapy of cancer. NK cells cytotoxicity is regulated by a balance between stimulatory and …