Cutaneous lupus erythematosus (CLE) is an autoimmune disease that can present as an
isolated skin disease or as a manifestation within the spectrum of systemic lupus …

The inefficient clearance of dying cells can result in the accumulation of apoptotic cell
remnants. This occurrence is considered an intrinsic defect that can cause the permanent …

Lupus erythematosus comprises a spectrum of autoimmune diseases that may affect various
organs (systemic lupus erythematosus [SLE]) or the skin only (cutaneous lupus …

Autoreactive B and T cells are present in healthy, autoimmunity-free individuals, but they are
kept in check by various regulatory mechanisms. In systemic lupus erythematosus (SLE) …

Cutaneous lupus erythematosus (CLE) is an inflammatory, autoimmune disease
encompassing a broad spectrum of subtypes including acute, subacute, chronic and …

Significant advances in the understanding of the molecular basis of innate immunity have
led to the identification of interferons (IFNs), particularly IFN-α, as central mediators in the …

Systemic lupus erythematosus (SLE) is a fairly heterogeneous autoimmune disease.
Impaired clearance functions for dying cells may explain accumulation of nuclear …

Systemic lupus erythematosus (SLE) is a prototype inflammatory autoimmune disease
resulting from autoimmune responses against nuclear autoantigens. During apoptosis many …

Lupus, Latin for “wolf,” is a term used to describe many dermatologic conditions, some of
which are related to underlying systemic lupus erythematosus, while others are distinct …

Systemic lupus erythematosus (SLE) is an autoimmune disease with very prominent chronic
inflammatory aspects that render into multiple symptoms and clinical signs. The precise …