[HTML][HTML] Is a lower dose of rivaroxaban required for Asians? A systematic review of a population pharmacokinetics and pharmacodynamics analysis of rivaroxaban
XQ Liu, ZR Li, CY Wang, YT Chen, Z Jiao - Pharmaceutics, 2023 - mdpi.com
Rivaroxaban has been widely used to prevent and treat various thromboembolic diseases
for more than a decade. However, whether a lower dose of rivaroxaban is required for …
for more than a decade. However, whether a lower dose of rivaroxaban is required for …
Direct oral anticoagulants plasma levels measurement: clinical usefulness from trials and real-world data
F Renon, A Rago, B Liccardo… - … in Thrombosis and …, 2021 - thieme-connect.com
Measurement of direct oral anticoagulants (DOACs) activity is not routinely necessary.
Indeed, evaluation of DOACs plasmatic concentration is discouraged for the majority of …
Indeed, evaluation of DOACs plasmatic concentration is discouraged for the majority of …
Associations among Plasma Concentrations of Edoxaban and M-4, Prothrombin Time, and the SLCO1B1* 15 Haplotype in Patients With Nonvalvular Atrial Fibrillation
J Nakagawa, T Kinjo, N Aiuchi, K Ueno… - Therapeutic Drug …, 2023 - journals.lww.com
Methods: The analyses included 152 patients with nonvalvular atrial fibrillation (NVAF)
undergoing AF catheter ablation. The CYP3A5* 3; CES1 c. 1168-33A> C, c. 257+ 885T> C; …
undergoing AF catheter ablation. The CYP3A5* 3; CES1 c. 1168-33A> C, c. 257+ 885T> C; …
The impact of advanced age on anticoagulant therapy for acute venous thromboembolism
L Lafaie, T Célarier, M Monreal, P Mismetti… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Management of venous thromboembolic events (VTE) has been completely
changed after the introduction of direct oral anticoagulants (DOAC). VTE is common in the …
changed after the introduction of direct oral anticoagulants (DOAC). VTE is common in the …
Rationale and design of a prospective study evaluating population pharmacokinetics and pharmacodynamics of rivaroxaban in Chinese patients with non-valvular …
XQ Liu, YF Zhang, HY Ding, MM Yan, MK Zhong… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Rivaroxaban is one of the most commonly used non-vitamin K antagonists for
stroke prevention in patients with non-valvular atrial fibrillation (NVAF). Different individual …
stroke prevention in patients with non-valvular atrial fibrillation (NVAF). Different individual …
[HTML][HTML] Effect of PCC on Thrombin Generation among Patients on Factor Xa Inhibitors with Major Bleeding or Needing Urgent Surgery (GAUGE): Design and …
JR Shaw, U Unachukwu, J Cyr, DM Siegal… - TH Open, 2023 - thieme-connect.com
Background Direct factor Xa inhibitors (FXaIs) account for most oral anticoagulant use and
FXaI-associated bleeding events are common. Clinicians have variable national and …
FXaI-associated bleeding events are common. Clinicians have variable national and …
Prospective randomized trial of antithrombotic strategies following great saphenous vein ablation using injectable polidocanol endovenous microfoam (Varithena)
J Yang, S Chung, S Srivatsa - Journal of Vascular Surgery: Venous and …, 2023 - Elsevier
Objective Postablation deep vein thrombosis (DVT) represents a potentially serious
complication after Varithena polidocanol endovenous microfoam (PEM) ablation. The …
complication after Varithena polidocanol endovenous microfoam (PEM) ablation. The …
Population pharmacokinetics of rivaroxaban in Chinese deep vein thrombosis patients and the exposure simulation for dosing recommendation
Z Li, S Yang, Z Hua, Y Lu, X Li - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
This study aimed to develop a population pharmacokinetic (PPK) model for rivaroxaban and
establish a model-based dosing guideline tailored to Chinese patients with deep vein …
establish a model-based dosing guideline tailored to Chinese patients with deep vein …
Impacts of pregnane X receptor and cytochrome P450 oxidoreductase gene polymorphisms on trough concentrations of apixaban in patients with non-valvular atrial …
J Nakagawa, T Kinjo, N Aiuchi, K Ueno… - European Journal of …, 2023 - Springer
Purpose We examined the impact of polymorphisms in genes encoding cytochrome P450
(CYP) 3A5 (gene code CYP3A5), P-glycoprotein (ABCB1), breast cancer resistance protein …
(CYP) 3A5 (gene code CYP3A5), P-glycoprotein (ABCB1), breast cancer resistance protein …
Safety of endoscopic ultrasound-guided tissue acquisition with uninterrupted direct oral anticoagulation in a swine model
AGG de Paredes, C Hartley… - Endoscopy …, 2023 - thieme-connect.com
Background and study aims The risk of bleeding with endoscopic ultrasound-guided tissue
acquisition (EUS-TA) in patients on uninterrupted antithrombotic agents is unknown. This …
acquisition (EUS-TA) in patients on uninterrupted antithrombotic agents is unknown. This …