The impact of tumor focality on prostate cancer (PCa) prognosis has been addressed in
several studies with conflicting results. Tumor foci from multifocal (MF) PCa can show highly …

Worldwide, prostate cancer (PC) is the second-most-frequently diagnosed male cancer and
the fifth-most-common cause of all cancer-related deaths. Suspicion of PC in a patient is …

Nuclear and optical dual-modality probes can be of great assistance in prostate cancer
localization, providing the means for both preoperative nuclear imaging and intraoperative …

Prostate cancer (PCa) is the most common malignant tumor in males. The benefits in terms
of overall reduction in specific mortality due to the widespread use of Prostate Specific …

Abstract Background Prostate cancer (PCa) is characterized by its tendency to be multifocal.
However, few studies have investigated the endogenous factors that explain the multifocal …

Prostate cancer (CaP) is often androgen-sensitive malignancy and regresses upon
inhibition of androgen signaling. However, CaP, nearly always develops androgen …

Differential classification of prostate cancer grade group (GG) 2 and 3 tumors remains
challenging, likely because of the subjective quantification of the percentage of Gleason …

This chapter will summarize novel understandings of the early molecular events in prostatic
carcinogenesis that may underlie both the genetic and clinical heterogeneity. Areas covered …

Prostate field cancerization denotes molecular alterations in histologically normal tissues
adjacent to tumors. Such alterations include deregulated protein expression, as we have …

Background: Biobanking of prostate carcinoma is particularly challenging due to the actual
cancer within the organ often without clear margins. Frozen sections are to date the only way …