An update on larynx cancer

CE Steuer, M El‐Deiry, JR Parks… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE Laryngeal cancer remains one of the most common
tumors of the respiratory tract. Fortunately, significant advancements have been made over …

[HTML][HTML] The role of microRNAs expression in laryngeal cancer

X Yu, Z Li - Oncotarget, 2015 - ncbi.nlm.nih.gov
MicroRNAs (miRs, miRs) is a class of small non-coding RNAs, which posttranscriptionally
regulate gene expression. Deregulated miRs are frequently obseved in patients with …

Impact of bile acids on the severity of laryngo‐pharyngeal reflux

E De Corso, S Baroni, G Salonna… - Clinical …, 2021 - Wiley Online Library
Objectives The primary end point of this study was to evaluate the impact of bile acids on
severity of laryngo‐pharyngeal reflux (LPR) and the possible correlation with esophagitis …

[HTML][HTML] Laryngopharyngeal reflux disease in the Greek general population, prevalence and risk factors

N Spantideas, E Drosou, A Bougea… - BMC Ear, Nose and …, 2015 - Springer
Background To assess the prevalence of laryngopharyngeal reflux (LPR) in the Greek
general population and its risk factors. Methods Questionnaire based epidemiological, adult …

[HTML][HTML] Inflammation and cancer: role of annexin A1 and FPR2/ALX in proliferation and metastasis in human laryngeal squamous cell carcinoma

TS Gastardelo, BR Cunha, LS Raposo, JV Maniglia… - PloS one, 2014 - journals.plos.org
The anti-inflammatory protein annexin A1 (ANXA1) has been associated with cancer
progression and metastasis, suggesting its role in regulating tumor cell proliferation. We …

[PDF][PDF] Higher levels of total pepsin and bile acids in the saliva as a possible risk factor for early laryngeal cancer

M Sereg-Bahar, A Jerin, I Hocevar-Boltezar - Radiology and oncology, 2015 - sciendo.com
Background. Gastroesophageal reflux is suspected to be an etiological factor in laryngeal
and pharyngeal cancer. The aim of this study was to establish, using a non-invasive method …

Laryngopharyngeal reflux and inflammatory responses in mucosal barrier dysfunction of the upper aerodigestive tract

D Liu, T Qian, S Sun, JJ Jiang - Journal of Inflammation Research, 2021 - Taylor & Francis
The upper aerodigestive tract (UAT) is the first line of defense against environmental
stresses such as antigens, microbes, inhalants, foods, etc., and mucins, intracellular …

[HTML][HTML] Pepsin promotes activation of epidermal growth factor receptor and downstream oncogenic pathways, at slightly acidic and neutral pH, in exposed …

PG Doukas, DP Vageli, CT Sasaki… - International Journal of …, 2021 - mdpi.com
Pepsin refluxate is considered a risk factor for laryngopharyngeal carcinogenesis. Non-
acidic pepsin was previously linked to an inflammatory and tumorigenic effect on …

[HTML][HTML] Reciprocal regulation of miR-1205 and E2F1 modulates progression of laryngeal squamous cell carcinoma

P Li, XJ Lin, Y Yang, AK Yang, JM Di, QW Jiang… - Cell Death & …, 2019 - nature.com
The burgeoning functions of many microRNAs (miRs) have been well study in cancer.
However, the level and function of miR-1205 in laryngeal squamous cell cancer remains …

Association of gastroesophageal reflux with malignancy of the upper aerodigestive tract in elderly patients

CA Riley, EL Wu, MC Hsieh, MJ Marino… - … –Head & Neck …, 2018 - jamanetwork.com
Importance Chronic inflammatory states have been linked to the development of
malignancy. Gastroesophageal reflux disease (GERD) is a known risk factor for esophageal …