miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay
High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …
[HTML][HTML] Characteristics of the cancer stem cell niche and therapeutic strategies
F Ju, MM Atyah, N Horstmann, S Gul, R Vago… - Stem Cell Research & …, 2022 - Springer
Distinct regions harboring cancer stem cells (CSCs) have been identified within the
microenvironment of various tumors, and as in the case of their healthy counterparts, these …
microenvironment of various tumors, and as in the case of their healthy counterparts, these …
[HTML][HTML] Identification and validation of an anoikis-associated gene signature to predict clinical character, stemness, IDH mutation, and immune filtration in …
Z Sun, Y Zhao, Y Wei, X Ding, C Tan… - Frontiers in …, 2022 - frontiersin.org
Background Glioblastoma (GBM) is the most prominent and aggressive primary brain tumor
in adults. Anoikis is a specific form of programmed cell death that plays a key role in tumor …
in adults. Anoikis is a specific form of programmed cell death that plays a key role in tumor …
MirDIP 5.2: tissue context annotation and novel microRNA curation
AC Hauschild, C Pastrello, GKA Ekaputeri… - Nucleic Acids …, 2023 - academic.oup.com
MirDIP is a well-established database that aggregates microRNA-gene human interactions
from multiple databases to increase coverage, reduce bias, and improve usability by …
from multiple databases to increase coverage, reduce bias, and improve usability by …
[PDF][PDF] Immune checkpoint blockade induces distinct alterations in the microenvironments of primary and metastatic brain tumors
L Sun, JC Kienzler, JG Reynoso, A Lee… - Journal of Clinical …, 2023 - Am Soc Clin Investig
In comparison with responses in recurrent glioblastoma (rGBM), the intracranial response of
brain metastases (BrM) to immune checkpoint blockade (ICB) is less well studied. Here, we …
brain metastases (BrM) to immune checkpoint blockade (ICB) is less well studied. Here, we …
[HTML][HTML] A bioinformatics-based analysis of an anoikis-related gene signature predicts the prognosis of patients with low-grade gliomas
S Zhao, H Chi, W Ji, Q He, G Lai, G Peng, X Zhao… - Brain Sciences, 2022 - mdpi.com
Low-grade glioma (LGG) is a highly aggressive disease in the skull. On the other hand,
anoikis, a specific form of cell death induced by the loss of cell contact with the extracellular …
anoikis, a specific form of cell death induced by the loss of cell contact with the extracellular …
[HTML][HTML] The hallmarks of glioblastoma: Heterogeneity, intercellular crosstalk and molecular signature of invasiveness and progression
F Torrisi, C Alberghina, S D'Aprile, AM Pavone… - Biomedicines, 2022 - mdpi.com
In 2021 the World Health Organization published the fifth and latest version of the Central
Nervous System tumors classification, which incorporates and summarizes a long list of …
Nervous System tumors classification, which incorporates and summarizes a long list of …
[HTML][HTML] Cannabigerol is a potential therapeutic agent in a novel combined therapy for glioblastoma
TT Lah, M Novak, MA Pena Almidon, O Marinelli… - Cells, 2021 - mdpi.com
Simple Summary Among primary brain tumours, glioblastoma is the most aggressive. As
early relapses are unavoidable despite standard-of-care treatment, the cannabinoids delta-9 …
early relapses are unavoidable despite standard-of-care treatment, the cannabinoids delta-9 …
Hypoxia‐driven M2‐polarized macrophages facilitate cancer aggressiveness and temozolomide resistance in glioblastoma
G Zhang, X Tao, B Ji, J Gong - Oxidative Medicine and Cellular …, 2022 - Wiley Online Library
Hypoxia‐induced M2 phenotypes of tumor associated macrophages (TAMs) promote the
development and chemoresistance of multiple types of cancers, including glioblastoma …
development and chemoresistance of multiple types of cancers, including glioblastoma …
[HTML][HTML] Glioma-associated microglia/macrophages (GAMs) in glioblastoma: Immune function in the tumor microenvironment and implications for immunotherapy
C Lin, N Wang, C Xu - Frontiers in Immunology, 2023 - frontiersin.org
Glioma is a mixed solid tumor composed of neoplastic and non-neoplastic components.
Glioma-associated macrophages and microglia (GAMs) are crucial elements of the glioma …
Glioma-associated macrophages and microglia (GAMs) are crucial elements of the glioma …