Mechanisms and disease consequences of nonalcoholic fatty liver disease

R Loomba, SL Friedman, GI Shulman - Cell, 2021 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …

NAFLD and cardiovascular diseases: a clinical review

P Kasper, A Martin, S Lang, F Kuetting… - Clinical research in …, 2021 - Springer
Non-alcoholic fatty liver DISEASE (NAFLD) is the most common chronic liver disease in
Western countries and affects approximately 25% of the adult population. Since NAFLD is …

[HTML][HTML] A randomized, controlled trial of the pan-PPAR agonist lanifibranor in NASH

SM Francque, P Bedossa, V Ratziu… - … England Journal of …, 2021 - Mass Medical Soc
Background Management of nonalcoholic steatohepatitis (NASH) is an unmet clinical need.
Lanifibranor is a pan-PPAR (peroxisome proliferator–activated receptor) agonist that …

[HTML][HTML] Non-alcoholic fatty liver disease: A patient guideline

SM Francque, G Marchesini, A Kautz, M Walmsley… - JHEP reports, 2021 - Elsevier
This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty
liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and …

Impact of non-invasive biomarkers on hepatology practice: past, present and future

QM Anstee, L Castera, R Loomba - Journal of hepatology, 2022 - Elsevier
Over the last two decades, there have been tremendous advances in the non-invasive
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …

Complications, morbidity and mortality of nonalcoholic fatty liver disease

A Mantovani, E Scorletti, A Mosca, A Alisi, CD Byrne… - Metabolism, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized public health
problem, affecting up to a quarter of the world's adult population. The burden of NAFLD is …

The fecal mycobiome in non-alcoholic fatty liver disease

M Demir, S Lang, P Hartmann, Y Duan, A Martin… - Journal of …, 2022 - Elsevier
Background & Aims Studies investigating the gut-liver axis have largely focused on bacteria,
whereas little is known about commensal fungi. We characterized fecal fungi in patients with …

AGA clinical practice update on screening and surveillance for hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: expert review

R Loomba, JK Lim, H Patton, HB El-Serag - Gastroenterology, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a leading etiology for chronic liver disease with
an immense public health impact and affects> 25% of the US and global population. Up to 1 …

[HTML][HTML] Non-alcoholic fatty liver disease: Definition and subtypes

SK Han, SK Baik, MY Kim - Clinical and molecular hepatology, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide, with a global prevalence of approximately 30%. However, the prevalence of …

Microbiota and fatty liver disease—the known, the unknown, and the future

S Lang, B Schnabl - Cell host & microbe, 2020 - cell.com
The liver communicates with the intestine via the portal vein, biliary system, and mediators in
the circulation. Microbes in the intestine maintain liver homeostasis but can also serve as a …