Stem cell bioprocessing: fundamentals and principles
MR Placzek, IM Chung, HM Macedo… - Journal of the …, 2009 - royalsocietypublishing.org
In recent years, the potential of stem cell research for tissue engineering-based therapies
and regenerative medicine clinical applications has become well established. In 2006 …
and regenerative medicine clinical applications has become well established. In 2006 …
Differential response of adult and embryonic mesenchymal progenitor cells to mechanical compression in hydrogels
Cells in the musculoskeletal system can respond to mechanical stimuli, supporting tissue
homeostasis and remodeling. Recent studies have suggested that mechanical stimulation …
homeostasis and remodeling. Recent studies have suggested that mechanical stimulation …
Thin films of functionalized multiwalled carbon nanotubes as suitable scaffold materials for stem cells proliferation and bone formation
In the field of regenerative medicine, human mesenchymal stem cells envisage extremely
promising applications, due to their ability to differentiate into a wide range of connective …
promising applications, due to their ability to differentiate into a wide range of connective …
Controlled release strategies for bone, cartilage, and osteochondral engineering—part I: recapitulation of native tissue healing and variables for the design of delivery …
The potential of growth factors to stimulate tissue healing through the enhancement of cell
proliferation, migration, and differentiation is undeniable. However, critical parameters on …
proliferation, migration, and differentiation is undeniable. However, critical parameters on …
Hydrogels for tissue engineering and delivery of tissue-inducing substances
B Baroli - Journal of pharmaceutical sciences, 2007 - Elsevier
This manuscript presents hydrogels (HGs) from a tissue engineering perspective being
especially written for those who are approaching this field by offering a concise but inclusive …
especially written for those who are approaching this field by offering a concise but inclusive …
The effect of mesenchymal stem cells delivered via hydrogel-based tissue engineered periosteum on bone allograft healing
Allografts remain the clinical “gold standard” for treatment of critical sized bone defects
despite minimal engraftment and∼ 60% long-term failure rates. Therefore, the development …
despite minimal engraftment and∼ 60% long-term failure rates. Therefore, the development …
Bioactive stratified polymer ceramic-hydrogel scaffold for integrative osteochondral repair
Due to the intrinsically poor repair potential of articular cartilage, injuries to this soft tissue do
not heal and require clinical intervention. Tissue engineered osteochondral grafts offer a …
not heal and require clinical intervention. Tissue engineered osteochondral grafts offer a …
Hierarchically designed agarose and poly (ethylene glycol) interpenetrating network hydrogels for cartilage tissue engineering
A new method for encapsulating cells in interpenetrating network (IPN) hydrogels of superior
mechanical integrity was developed. In this study, two biocompatible materials—agarose …
mechanical integrity was developed. In this study, two biocompatible materials—agarose …
Stem cell therapy–Hype or hope? A review
RR Nadig - Journal of Conservative Dentistry, 2009 - journals.lww.com
While the regeneration of a lost tissue is known to mankind for several years, it is only in the
recent past that research on regenerative medicine/dentistry has gained momentum and …
recent past that research on regenerative medicine/dentistry has gained momentum and …
Matrix metalloproteinase (MMP)-degradable tissue engineered periosteum coordinates allograft healing via early stage recruitment and support of host …
Y Li, MD Hoffman, DSW Benoit - Biomaterials, 2021 - Elsevier
Despite serving as the clinical “gold standard” treatment for critical size bone defects,
decellularized allografts suffer from long-term failure rates of~ 60% due to the absence of the …
decellularized allografts suffer from long-term failure rates of~ 60% due to the absence of the …