[HTML][HTML] Inflammatory cerebrospinal fluid markers in schizophrenia spectrum disorders: A systematic review and meta-analysis of 69 studies with 5710 participants

N Warren, C O'Gorman, I Horgan, M Weeratunga… - Schizophrenia …, 2024 - Elsevier
Background There is increasing evidence of immune dysregulation and neuroinflammation
occurring in schizophrenia. The aim of this study is to combine studies on routine CSF …

Biomarkers of bipolar disorder in late life: an evidence-based systematic review

R Chancel, J Lopez-Castroman, E Baca-Garcia… - Current Psychiatry …, 2024 - Springer
Abstract Purpose of Review Review the current evidence on biomarkers for bipolar disorder
in the older adults. We conducted a systematic search of PubMed MEDLINE, PsycINFO, and …

[HTML][HTML] Complement proteins are elevated in blood serum but not CSF in clinical high-risk and antipsychotic-naïve first-episode psychosis

VL Cropley, M Kittel, M Heurich, M Föcking… - Brain, Behavior, and …, 2023 - Elsevier
Alterations in the complement system have been reported in some people with psychotic
disorder, including in pre-psychotic individuals, suggesting that complement pathway …

[HTML][HTML] Association of symptom severity and cerebrospinal fluid alterations in recent onset psychosis in schizophrenia-spectrum disorders–An individual patient data …

M Campana, V Yakimov, J Moussiopoulou… - Brain, Behavior, and …, 2024 - Elsevier
Neuroinflammation and blood-cerebrospinal fluid barrier (BCB) disruption could be key
elements in schizophrenia-spectrum disorderś (SSDs) etiology and symptom modulation …

Inflammatory blood biomarkers are associated with long-term clinical disease severity in Parkinson's disease

DH Hepp, TA van Wageningen, KL Kuiper… - International journal of …, 2023 - mdpi.com
An altered immune response has been identified as a pathophysiological factor in
Parkinson's disease (PD). We aimed to identify blood immunity-associated proteins that …

A critical appraisal of blood-based biomarkers for Alzheimer's disease

S Lista, M Mapstone, F Caraci, E Emanuele… - Ageing Research …, 2024 - Elsevier
Biomarkers that predict the clinical onset of Alzheimer's disease (AD) enable the
identification of individuals in the early, preclinical stages of the disease. Detecting AD at this …

Effects of estrogen and progesterone on neuroactive steroids and cytokines in patients with suicidality

JC Barone, E Wenzel, V Alluri, D Moriarity… - …, 2023 - Elsevier
Background In ovulating psychiatric patients experiencing suicidality, suicidal ideation (SI)
often peaks perimenstrually. Our recent double-blind, placebo-controlled, crossover …

Depression and HIV: a scoping review in search of neuroimmune biomarkers

A Mudra Rakshasa-Loots - Brain Communications, 2023 - academic.oup.com
People with HIV are at increased risk for depression, though the neurobiological
mechanisms underlying this are unclear. In the last decade, there has been a substantial …

The Role of Inflammation in Depression and Beyond: A Primer for Clinicians

EA Calagua-Bedoya, V Rajasekaran, L De Witte… - Current Psychiatry …, 2024 - Springer
The current evidence does not fully support inflammation, infections or autoimmunity as
possible etiologies of depression. The available studies have numerous confounders that …

Chronic immunosuppression across 12 months and high ability of acute and subacute CNS-injury biomarker concentrations to identify individuals with complicated …

GJB Clarke, T Follestad, T Skandsen… - Journal of …, 2024 - Springer
Background Identifying individuals with intracranial injuries following mild traumatic brain
injury (mTBI), ie complicated mTBI cases, is important for follow-up and prognostication. The …