Objective We aimed to assess the treatment response of infantile‐onset epileptic spasms
(ES) in CDKL5 deficiency disorder (CDD) vs other etiologies. Methods We evaluated …

Purpose To assess epilepsy, motor function, cognitive, sleep, and quality of life outcomes
and their predictors in a follow-up cohort with West syndrome (WS) at≥ 5 years of age …

Corticosteroids have been used for the treatment of patients with epilepsy for more than 6
decades, based on the hypothesis of inflammation in the genesis and/or promotion of …

Objective To develop an improved interictal electroencephalogram (EEG) grading scale for
children with infantile spasms founded on elements with adequate inter-rater reliability (IRR) …

Objective To compare the effectiveness and cost‐effectiveness of adrenocorticotropic
hormone (ACTH) and oral steroids as first‐line treatment for infantile spasm resolution, we …

Objective To compare the therapeutic effectiveness of oral corticosteroids with that of
adrenocorticotrophic hormone for infantile spasms. Methods PubMed, Embase, Scopus, and …

Objective The aim of this study was to determine whether selection of treatment for children
with infantile spasms (IS) varies by race/ethnicity. Methods The prospective US National …

Epileptic Spasms (ES) is a type of seizure usually occurring in the context of a severe
childhood epileptic syndrome associated to significant Electroencephalogram (EEG) …

Aim To compare the efficacy and safety of prednisolone/prednisone and adrenocorticotropic
hormone (ACTH) in the treatment of infantile spasms using a meta‐analysis of randomized …

Background and Objectives Pathogenic variants in STXBP1 are among the major genetic
causes of neurodevelopmental disorders. Despite the increasing number of individuals …