Epileptic spasms in CDKL5 deficiency disorder: Delayed treatment and poor response to first‐line therapies
HE Olson, S Demarest, E Pestana‐Knight… - …, 2023 - Wiley Online Library
Objective We aimed to assess the treatment response of infantile‐onset epileptic spasms
(ES) in CDKL5 deficiency disorder (CDD) vs other etiologies. Methods We evaluated …
(ES) in CDKL5 deficiency disorder (CDD) vs other etiologies. Methods We evaluated …
Long-term epilepsy control, motor function, cognition, sleep and quality of life in children with West syndrome
S Bhanudeep, P Madaan, N Sankhyan, L Saini… - Epilepsy Research, 2021 - Elsevier
Purpose To assess epilepsy, motor function, cognitive, sleep, and quality of life outcomes
and their predictors in a follow-up cohort with West syndrome (WS) at≥ 5 years of age …
and their predictors in a follow-up cohort with West syndrome (WS) at≥ 5 years of age …
Corticosteroids in childhood epilepsies: A systematic review
LL Becker, AM Kaindl - Frontiers in Neurology, 2023 - frontiersin.org
Corticosteroids have been used for the treatment of patients with epilepsy for more than 6
decades, based on the hypothesis of inflammation in the genesis and/or promotion of …
decades, based on the hypothesis of inflammation in the genesis and/or promotion of …
[HTML][HTML] A reliable interictal EEG grading scale for children with infantile spasms–The 2021 BASED score
JR Mytinger, J Vidaurre, M Moore-Clingenpeel… - Epilepsy Research, 2021 - Elsevier
Objective To develop an improved interictal electroencephalogram (EEG) grading scale for
children with infantile spasms founded on elements with adequate inter-rater reliability (IRR) …
children with infantile spasms founded on elements with adequate inter-rater reliability (IRR) …
Cost‐effectiveness of adrenocorticotropic hormone versus oral steroids for infantile spasms
I Sanchez Fernandez, M Amengual‐Gual… - …, 2021 - Wiley Online Library
Objective To compare the effectiveness and cost‐effectiveness of adrenocorticotropic
hormone (ACTH) and oral steroids as first‐line treatment for infantile spasm resolution, we …
hormone (ACTH) and oral steroids as first‐line treatment for infantile spasm resolution, we …
Effectiveness of corticosteroids versus adrenocorticotropic hormone for infantile spasms: a systematic review and meta‐analysis
YH Chang, C Chen, SH Chen… - Annals of Clinical and …, 2019 - Wiley Online Library
Objective To compare the therapeutic effectiveness of oral corticosteroids with that of
adrenocorticotrophic hormone for infantile spasms. Methods PubMed, Embase, Scopus, and …
adrenocorticotrophic hormone for infantile spasms. Methods PubMed, Embase, Scopus, and …
Inequities in therapy for infantile spasms: a call to action
FM Baumer, JR Mytinger, K Neville… - Annals of …, 2022 - Wiley Online Library
Objective The aim of this study was to determine whether selection of treatment for children
with infantile spasms (IS) varies by race/ethnicity. Methods The prospective US National …
with infantile spasms (IS) varies by race/ethnicity. Methods The prospective US National …
Three different scenarios for epileptic spasms
L Fusco, D Serino, ME Santarone - Epilepsy & Behavior, 2020 - Elsevier
Epileptic Spasms (ES) is a type of seizure usually occurring in the context of a severe
childhood epileptic syndrome associated to significant Electroencephalogram (EEG) …
childhood epileptic syndrome associated to significant Electroencephalogram (EEG) …
Prednisolone/prednisone as adrenocorticotropic hormone alternative for infantile spasms: a meta‐analysis of randomized controlled trials
S Li, X Zhong, S Hong, T Li… - Developmental Medicine & …, 2020 - Wiley Online Library
Aim To compare the efficacy and safety of prednisolone/prednisone and adrenocorticotropic
hormone (ACTH) in the treatment of infantile spasms using a meta‐analysis of randomized …
hormone (ACTH) in the treatment of infantile spasms using a meta‐analysis of randomized …
Natural History and Developmental Trajectories of Individuals With Disease-Causing Variants in STXBP1
KM Thalwitzer, JH Driedger, J Xian, A Saffari… - Neurology, 2023 - AAN Enterprises
Background and Objectives Pathogenic variants in STXBP1 are among the major genetic
causes of neurodevelopmental disorders. Despite the increasing number of individuals …
causes of neurodevelopmental disorders. Despite the increasing number of individuals …