In the present research, a zone fluidics-based automated sensor for the analysis of captopril
in in vitro dissolution samples is reported. Captopril is reacted under flow conditions with Ni …

The overarching theme of this work is the investigation and development of in vitro and in
silico methods used to characterize inhaled pharmaceutical aerosols. The ultimate aim is to …

Pulmonary drug delivery has been used for decades to treat local diseases like asthma.
When using the pulmonary route to deliver drugs, several important lung features are being …

1.2. 1 Airway Geometry 1.2. 1.1 Realistic and semi-realistic extrathoracic geometries 1.2. 1.2
Idealized extrathoracic geometries 1.2. 1.3 In vitro measures of thoracic deposition 1.2. 2 …

Respiratory exposure of humans to environmental and therapeutic nanoparticles repeatedly
occurs at relatively low concentrations. To identify adverse effects of particle accumulation …

Factors affecting deposition may be patient‐specific such as inspiratory profile, lung luminal
conditions, and airway geometry or drug product dependent such as inhalation device or …

Today there are no recommended dissolution methods for use in the development of
newinhalable drugs. In the absence of such tailored methods, standard dissolution test …

Pseudomonas aeruginosa (PA) is the predominant pathogen in chronic lung infections of
cystic fibrosis (CF) patients. The most important mechanism of adaptation of PA to host …

The respiratory route is widely acceptable currently because it has a maximum absorptive
area of up to 100 m2 with good blood supply. Many diseases like asthma, asthmatic rhinitis …

Background Tuberculosis (TB), a global health problem caused by Mycobacterium
tuberculosis, mainly affects the lungs and spreads to other organs. Rifampicin is a potent …