Revisiting the cholinergic hypothesis in the development of Alzheimer's disease
LA Craig, NS Hong, RJ McDonald - Neuroscience & Biobehavioral …, 2011 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia affecting the elderly
population today; however, there is currently no accurate description of the etiology of this …
population today; however, there is currently no accurate description of the etiology of this …
Repairing the human brain after stroke: I. Mechanisms of spontaneous recovery
SC Cramer - Annals of neurology, 2008 - Wiley Online Library
Stroke remains a leading cause of adult disability. Some degree of spontaneous behavioral
recovery is usually seen in the weeks after stroke onset. Variability in recovery is substantial …
recovery is usually seen in the weeks after stroke onset. Variability in recovery is substantial …
Increased brain injury and worsened neurological outcome in interleukin-4 knockout mice after transient focal cerebral ischemia
Background and Purpose—Stroke causes brain injury with activation of an inflammatory
response that can contribute to injury. We tested the hypothesis that the anti-inflammatory …
response that can contribute to injury. We tested the hypothesis that the anti-inflammatory …
Experimental models of brain ischemia: a review of techniques, magnetic resonance imaging, and investigational cell-based therapies
A Canazza, L Minati, C Boffano, E Parati… - Frontiers in …, 2014 - frontiersin.org
Stroke continues to be a significant cause of death and disability worldwide. Although major
advances have been made in the past decades in prevention, treatment, and rehabilitation …
advances have been made in the past decades in prevention, treatment, and rehabilitation …
Myricetin ameliorates brain injury and neurological deficits via Nrf2 activation after experimental stroke in middle-aged rats
S Wu, Y Yue, A Peng, L Zhang, J Xiang, X Cao… - Food & Function, 2016 - pubs.rsc.org
The aim of our study was to investigate the protective effects and underlying mechanisms of
myricetin, a bioactive food compound, on brain injury and neurological deficits after ischemic …
myricetin, a bioactive food compound, on brain injury and neurological deficits after ischemic …
Gait impairment in a rat model of focal cerebral ischemia
S Parkkinen, FJ Ortega, K Kuptsova… - Stroke research and …, 2013 - Wiley Online Library
The availability of proper tests for gait evaluation following cerebral ischemia in rats has
been limited. The automated, quantitative CatWalk system, which was initially designed to …
been limited. The automated, quantitative CatWalk system, which was initially designed to …
Propofol pretreatment attenuates aquaporin-4 over-expression and alleviates cerebral edema after transient focal brain ischemia reperfusion in rats
YY Zheng, YP Lan, HF Tang, SM Zhu - Anesthesia & Analgesia, 2008 - journals.lww.com
BACKGROUND: Cerebral edema is a major threat for stroke victims. Most studies have
focused on the neuroprotective activities of propofol, addressing infarct volume rather than …
focused on the neuroprotective activities of propofol, addressing infarct volume rather than …
Combined contrast-enhanced ultrasound and rt-PA treatment is safe and improves impaired microcirculation after reperfusion of middle cerebral artery occlusion
M Nedelmann, N Ritschel, S Doenges… - Journal of Cerebral …, 2010 - journals.sagepub.com
In monitoring of recanalization and in sonothrombolysis, contrast-enhanced ultrasound
(CEUS) is applied in extended time protocols. As extended use may increase the probability …
(CEUS) is applied in extended time protocols. As extended use may increase the probability …
Propofol attenuates cerebral ischemia/reperfusion injury partially using heme oxygenase-1
C Liang, J Cang, H Wang, Z Xue - Journal of Neurosurgical …, 2013 - journals.lww.com
Background: To investigate the protective effects of propofol in brain ischemia/reperfusion
injury and the role of heme oxygenase-1 (HO-1) in this process. Methods: Sprague-Dawley …
injury and the role of heme oxygenase-1 (HO-1) in this process. Methods: Sprague-Dawley …
[HTML][HTML] Secretomes of apoptotic mononuclear cells ameliorate neurological damage in rats with focal ischemia
The pursuit of targeting multiple pathways in the ischemic cascade of cerebral stroke is a
promising treatment option. We examined the regenerative potential of conditioned medium …
promising treatment option. We examined the regenerative potential of conditioned medium …