Metabolic syndrome and cardiovascular diseases: Going beyond traditional risk factors

JL Silveira Rossi, SM Barbalho… - Diabetes/metabolism …, 2022 - Wiley Online Library
Metabolic syndrome (MS) is a chronic non‐infective syndrome characterised clinically by a
set of vascular risk factors that include insulin resistance, hypertension, abdominal obesity …

Dietary antioxidant supplements and uric acid in chronic kidney disease: a review

S Roumeliotis, A Roumeliotis, E Dounousi… - Nutrients, 2019 - mdpi.com
Increased serum levels of uric acid have been associated with the onset and development of
chronic kidney disease (CKD), cardiovascular disease, and mortality, through several …

Injectable and self-healing chitosan-based hydrogel with MOF-loaded α-lipoic acid promotes diabetic wound healing

Q Li, K Liu, T Jiang, S Ren, Y Kang, W Li, H Yao… - Materials Science and …, 2021 - Elsevier
The difficulty of wound healing in patients with diabetes mellitus remains a considerable
challenge for clinical and scientific research. To address the problem of poor healing that …

Mechanisms of cardiovascular disorders in patients with chronic kidney disease: a process related to accelerated senescence

J Carracedo, M Alique, C Vida, G Bodega… - Frontiers in cell and …, 2020 - frontiersin.org
Cardiovascular diseases (CVDs), especially those involving a systemic inflammatory
process such as atherosclerosis, remain the leading cause of morbidity and mortality in …

A-lipoic acid alleviates folic acid-induced renal damage through inhibition of ferroptosis

X Li, YU Zou, YY Fu, J Xing, KY Wang, PZ Wan… - Frontiers in …, 2021 - frontiersin.org
Folic acid (FA)-induced acute kidney injury (AKI) is characterized by the disturbance of redox
homeostasis, resulting in massive tubular necrosis and inflammation. Α-lipoic acid (LA), as …

Hormesis and oxidative distress: Pathophysiology of reactive oxygen species and the open question of antioxidant modulation and supplementation

M Nitti, B Marengo, AL Furfaro, MA Pronzato… - Antioxidants, 2022 - mdpi.com
Alterations of redox homeostasis leads to a condition of resilience known as hormesis that is
due to the activation of redox-sensitive pathways stimulating cell proliferation, growth …

Association between the composite dietary antioxidant index and chronic kidney disease: Evidence from NHANES 2011–2018

M Wang, Z Huang, Y Zhu, P He, QL Fan - Food & Function, 2023 - pubs.rsc.org
Objectives: There is growing evidence that antioxidant-rich diets protect against chronic
kidney disease (CKD). However, the relationship between the Composite Dietary …

Developmental origins of kidney disease: why oxidative stress matters?

CN Hsu, YL Tain - Antioxidants, 2020 - mdpi.com
The “developmental origins of health and disease” theory indicates that many adult-onset
diseases can originate in the earliest stages of life. The developing kidney has emerged as …

The anti-nephritic activity of a polysaccharide from okra (Abelmoschus esculentus (L.) Moench) via modulation of AMPK-Sirt1-PGC-1α signaling axis mediated anti …

Z Liao, J Zhang, J Wang, T Yan, F Xu, B Wu… - International journal of …, 2019 - Elsevier
Diabetic nephropathy (DN) with high morbidity and mortality is one of the most severe
diabetes complications and affects nearly one-third of people with diabetes. Our present …

Unfavorable effects of peritoneal dialysis solutions on the peritoneal membrane: the role of oxidative stress

S Roumeliotis, E Dounousi, M Salmas, T Eleftheriadis… - Biomolecules, 2020 - mdpi.com
One of the main limitations to successful long-term use of peritoneal dialysis (PD) as a renal
replacement therapy is the harmful effects of PD solutions to the structure and function of the …