Platelets and infections–complex interactions with bacteria

H Hamzeh-Cognasse, P Damien, A Chabert… - Frontiers in …, 2015 - frontiersin.org
Platelets can be considered sentinels of vascular system due to their high number in the
circulation and to the range of functional immunoreceptors they express. Platelets express a …

Caspase-3 mediates in part hippocampal apoptosis in sepsis

CM Comim, T Barichello, D Grandgirard… - Molecular …, 2013 - Springer
The brain is one of the first organs affected during sepsis development resulting in apoptosis
for a short-term and cognitive impairment for a long-term. Despite its importance, the …

Sepsis induces apoptotic cell death in different regions of the brain in a rat model of sepsis

İM Kafa, M Uysal, S Bakırcı, A Kurt - 2010 - acikerisim.uludag.edu.tr
Sepsis occurs in 14-37% of patients admitted to intensive care units and sepsis associated
encephalopathy (SAE) is its severe complication. In an attempt to provide insight into the …

Pegylated G‐CSF inhibits blood cell depletion, increases platelets, blocks splenomegaly, and improves survival after whole‐body ionizing irradiation but not after …

JG Kiang, M Zhai, PJ Liao, DL Bolduc… - Oxidative medicine …, 2014 - Wiley Online Library
Exposure to ionizing radiation alone (radiation injury, RI) or combined with traumatic tissue
injury (radiation combined injury, CI) is a crucial life‐threatening factor in nuclear and …

Programmed death 1 expression as a marker for immune and physiological dysfunction in the critically ill surgical patient

SF Monaghan, RK Thakkar, ML Tran, X Huang… - Shock, 2012 - journals.lww.com
Abstract Programmed death 1 (PD-1) is an inhibitor protein receptor for the immune system
and has been shown to be upregulated in animal models of critical illness as well as after …

Adaptive redox response of mesenchymal stromal cells to stimulation with lipopolysaccharide inflammagen: mechanisms of remodeling of tissue barriers in sepsis

NV Gorbunov, BR Garrison… - Oxidative medicine …, 2013 - Wiley Online Library
Acute bacterial inflammation is accompanied by excessive release of bacterial toxins and
production of reactive oxygen and nitrogen species (ROS and RNS), which ultimately results …

乌司他丁联合胸腺肽α1 治疗对脓毒症患者疗效的荟萃分析

陈子盛, 傅应云, 林少雄, 刘盛国, 何正强… - 中国中西医结合急救 …, 2012 - cqvip.com
目的评价乌司他丁(UTI) 联合胸腺肽仅, 对脓毒症患者免疫状态和疗效, 预后的影响.
方法通过关键词, 主题词, 引文追溯等途径检索PubMed, Elsevier-SDOL, Embase, Cochrane …

Identification of potential biomarkers of sepsis using bioinformatics analysis

YX Yang, L Li - Experimental and Therapeutic …, 2017 - spandidos-publications.com
Sepsis is defined as the systemic inflammatory response to infection and is one of the
leading causes of mortality in critically ill patients. The goal of the present study is to …

Transglutaminase 2 at the crossroads between cell death and survival

M Piacentini, M D'Eletto, L Falasca… - … in enzymology and …, 2011 - Wiley Online Library
198 PIACENTINI MAURO ET AL. cross-linking, via ε-(-glutamyl) lysine bonds, or through the
incorporation of primary amines, at the level peptide-bound glutamine residues [1]. The …

Rough‐Form Lipopolysaccharide Increases Apoptosis in Human CD4+ and CD8+ T Lymphocytes

JS Nielsen, A Larsson, T Ledet, M Turina… - Scandinavian …, 2012 - Wiley Online Library
Immunosuppression induced by lymphocyte apoptosis is considered an important factor in
the pathogenesis of sepsis and has been demonstrated in both animal models of …