A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

W Checkley, AC White, D Jaganath… - The Lancet Infectious …, 2015 - thelancet.com
Cryptosporidium spp are well recognised as causes of diarrhoeal disease during
waterborne epidemics and in immunocompromised hosts. Studies have also drawn …

Cryptosporidium and Giardia in Africa: current and future challenges

SA Squire, U Ryan - Parasites & vectors, 2017 - Springer
Cryptosporidium and Giardia are important causes of diarrhoeal illness. Adequate
knowledge of the molecular diversity and geographical distribution of these parasites and …

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case …

KL Kotloff, JP Nataro, WC Blackwelder, D Nasrin… - The lancet, 2013 - thelancet.com
Background Diarrhoeal diseases cause illness and death among children younger than 5
years in low-income countries. We designed the Global Enteric Multicenter Study (GEMS) to …

Cryptosporidium pathogenicity and virulence

M Bouzid, PR Hunter, RM Chalmers… - Clinical microbiology …, 2013 - Am Soc Microbiol
Cryptosporidium is a protozoan parasite of medical and veterinary importance that causes
gastroenteritis in a variety of vertebrate hosts. Several studies have reported different …

Enteric protozoa in the developed world: a public health perspective

SM Fletcher, D Stark, J Harkness… - Clinical microbiology …, 2012 - Am Soc Microbiol
Several enteric protozoa cause severe morbidity and mortality in both humans and animals
worldwide. In developed settings, enteric protozoa are often ignored as a cause of diarrheal …

Burden of disease from cryptosporidiosis

DAT Shirley, SN Moonah, KL Kotloff - Current opinion in infectious …, 2012 - journals.lww.com
Burden of disease from cryptosporidiosis : Current Opinion in Infectious Diseases Burden of
disease from cryptosporidiosis : Current Opinion in Infectious Diseases Log in or Register …

Global Distribution, Public Health and Clinical Impact of the Protozoan Pathogen Cryptosporidium

L Putignani, D Menichella - Interdisciplinary perspectives on …, 2010 - Wiley Online Library
Cryptosporidium spp. are coccidians, oocysts‐forming apicomplexan protozoa, which
complete their life cycle both in humans and animals, through zoonotic and anthroponotic …

Prevalence of gastrointestinal pathogens in developed and developing countries: systematic review and meta-analysis

SM Fletcher, ML McLaws… - Journal of public health …, 2013 - journals.sagepub.com
Diarrhoeal illness is a leading cause of child mortality and morbidity worldwide. There are
no precise or current estimates of the types and prevalence of pathogens associated with …

High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial

B Amadi, M Mwiya, S Sianongo, L Payne… - BMC infectious …, 2009 - Springer
Background Treatment of cryptosporidiosis in HIV infected children has proved difficult and
unsatisfactory with no drugs having demonstrable efficacy in controlled trials except …

Severe acute malnutrition and infection

KDJ Jones, JA Berkley - Paediatrics and international child health, 2014 - Taylor & Francis
Severe acute malnutrition (SAM) is associated with increased severity of common infectious
diseases, and death amongst children with SAM is almost always as a result of infection …