Potential treatment targets for migraine: emerging options and future prospects

CC Chiang, F Porreca, CE Robertson… - The Lancet …, 2024 - thelancet.com
Migraine is a leading cause of disability worldwide. Despite the recent approval of several
calcitonin gene-related peptide-targeted therapies, many people with migraine do not …

Considerations for hormonal therapy in migraine patients: a critical review of current practice

R van Lohuizen, J Paungarttner, C Lampl… - Expert Review of …, 2024 - Taylor & Francis
Introduction Migraine, a neurovascular headache disorder, is a leading cause of disability
worldwide. Within the multifaceted pathophysiology of migraine, hormonal fluctuations play …

Exploring the Connection between Migraines and Pregnancy: The Impact of Physical Activity on Symptom Management

M Lackovic, M Jankovic, S Mihajlovic, Z Milovanovic… - Medicina, 2023 - mdpi.com
Migraine is a prevalent neurological disorder that significantly impacts the quality of life for
affected individuals. The pathogenesis behind migraines is not yet fully understood, but …

[HTML][HTML] Oxytocin and vasopressin signaling in health and disease

M Perisic, K Woolcock, A Hering, H Mendel… - Trends in Biochemical …, 2024 - cell.com
Neurohypophysial peptides are ancient and evolutionarily highly conserved neuropeptides
that regulate many crucial physiological functions in vertebrates and invertebrates. The …

Molecular and cellular neurobiology of circadian and circannual rhythms in migraine: A narrative review

N Imai - International Journal of Molecular Sciences, 2023 - mdpi.com
Migraine—a primary headache—has circadian and circannual rhythms in the onset of
attacks. The circadian and circannual rhythms involve the hypothalamus, which is strongly …

PACAP-38 and sex hormones in women with migraine: exploratory analysis of a cross-sectional, matched cohort study

E Storch, LH Overeem, M Terhart, MP Fitzek… - The Journal of …, 2024 - Springer
Background Endogeneous and exogeneous sex hormones can impact the frequency and
severity of migraine attacks, but the underlying mechanisms are poorly understood. In this …

Female-selective mechanisms promoting migraine

S Singh, CM Kopruszinski, M Watanabe… - The Journal of …, 2024 - Springer
Sexual dimorphism has been revealed for many neurological disorders including chronic
pain. Prelicinal studies and post-mortem analyses from male and female human donors …

Understanding the Biological Relationship between Migraine and Depression

A Viudez-Martínez, AB Torregrosa, F Navarrete… - Biomolecules, 2024 - mdpi.com
Migraine is a highly prevalent neurological disorder. Among the risk factors identified,
psychiatric comorbidities, such as depression, seem to play an important role in its onset …

Pharmacological management of migraine: current strategies and future directions

L Pellesi, TP Do, A Hougaard - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Migraine is a complex neurological disorder that affects a significant portion of
the global population. As traditional pharmacological approaches often fall short in …

Breastfeeding-Related Adverse Drug Reactions of Triptans: A Descriptive Analysis Using Four Pharmacovigilance Databases

M Conijn, V Maas, M van Tuyl, M Ceulemans… - Breastfeeding …, 2024 - liebertpub.com
Objective: Migraine attacks are common in women of reproductive age. Although attacks are
often less severe and less frequent during pregnancy, they regularly reoccur shortly after …