[HTML][HTML] Is arsenic exposure a risk factor for metabolic syndrome? a review of the potential mechanisms
Exposure to arsenic in drinking water is a worldwide health problem. This pollutant is
associated with increased risk of developing chronic diseases, including metabolic …
associated with increased risk of developing chronic diseases, including metabolic …
[HTML][HTML] ASBT (SLC10A2): A promising target for treatment of diseases and drug discovery
N Yang, YQ Dong, GX Jia, SM Fan, SZ Li… - Biomedicine & …, 2020 - Elsevier
Bile acids has gradually become a new focus in various diseases, and ASBT as a
transporter responsible for the reabsorption of ileal bile acids, is a key hinge associated to …
transporter responsible for the reabsorption of ileal bile acids, is a key hinge associated to …
Intermittent hypoxia training in prediabetes patients: Beneficial effects on glucose homeostasis, hypoxia tolerance and gene expression
TV Serebrovska, AG Portnychenko… - Experimental …, 2017 - journals.sagepub.com
The present study aimed at examining beneficial effects of intermittent hypoxia training (IHT)
under prediabetic conditions. We investigate the effects of three-week IHT on blood glucose …
under prediabetic conditions. We investigate the effects of three-week IHT on blood glucose …
[HTML][HTML] Molecular insulin actions are sexually dimorphic in lipid metabolism
The increment in energy-dense food and low physical activity has contributed to the current
obesity pandemic, which is more prevalent in women than in men. Insulin is an anabolic …
obesity pandemic, which is more prevalent in women than in men. Insulin is an anabolic …
The therapeutic and nutraceutical potential of agmatine, and its enhanced production using Aspergillus oryzae
N Akasaka, S Fujiwara - Amino Acids, 2020 - Springer
Agmatine, a natural polyamine produced from arginine by arginine decarboxylase, was first
discovered in 1910, but its physiological significance was disregarded for a century. The …
discovered in 1910, but its physiological significance was disregarded for a century. The …
The association between the differential expression of lncRNA and type 2 diabetes mellitus in people with hypertriglyceridemia
S Yan, N Yao, X Li, M Sun, Y Yang, W Cui… - International Journal of …, 2023 - mdpi.com
Compared with diabetic patients with normal blood lipid, diabetic patients with dyslipidemia
such as high triglycerides have a higher risk of clinical complications, and the disease is …
such as high triglycerides have a higher risk of clinical complications, and the disease is …
Cyanidin Stimulates Insulin Secretion and Pancreatic β-Cell Gene Expression through Activation of l-type Voltage-Dependent Ca2+ Channels
Cyanidin is a natural anthocyanidin present in fruits and vegetables with anti-diabetic
properties including stimulation of insulin secretion. However, its mechanism of action …
properties including stimulation of insulin secretion. However, its mechanism of action …
[PDF][PDF] Blocking Ca2+ channel β3 subunit reverses diabetes
Summary Voltage-gated Ca 2+ channels (Ca v) are essential for pancreatic beta cell
function as they mediate Ca 2+ influx, which leads to insulin exocytosis. The β3 subunit of …
function as they mediate Ca 2+ influx, which leads to insulin exocytosis. The β3 subunit of …
Regulation of cAMP accumulation and activity by distinct phosphodiesterase subtypes in INS-1 cells and human pancreatic β-cells
Pancreatic β-cells express multiple phosphodiesterase (PDE) subtypes, but the specific
roles for each in β-cell function, particularly in humans, is not clear. We evaluated the …
roles for each in β-cell function, particularly in humans, is not clear. We evaluated the …
Insulin release mechanism modulated by toxins isolated from animal venoms: from basic research to drug development prospects
BE Sarmiento, LF Santos Menezes, EF Schwartz - Molecules, 2019 - mdpi.com
Venom from mammals, amphibians, snakes, arachnids, sea anemones and insects provides
diverse sources of peptides with different potential medical applications. Several of these …
diverse sources of peptides with different potential medical applications. Several of these …