[HTML][HTML] The role of T cells in systemic sclerosis: An update

LI Sakkas, DP Bogdanos - Immuno, 2022 - mdpi.com
Systemic sclerosis (SSc) is a chronic disease characterized by microvasculopathy,
autoantibodies (autoAbs), and fibrosis. The pathogenesis of the disease is incompletely …

[HTML][HTML] Umbilical-Cord-Derived Mesenchymal Stromal Cells Modulate 26 Out of 41 T Cell Subsets from Systemic Sclerosis Patients

P Laranjeira, F Dos Santos, MJ Salvador, IN Simões… - Biomedicines, 2023 - mdpi.com
Systemic sclerosis (SSc) is an immune-mediated disease wherein T cells are particularly
implicated, presenting a poor prognosis and limited therapeutic options. Thus, mesenchymal …

[HTML][HTML] Prediction of herbal medicines based on immune cell infiltration and immune-and ferroptosis-related gene expression levels to treat valvular atrial fibrillation

F Jiang, W Zhang, H Lu, M Tan, Z Zeng, Y Song… - Frontiers in …, 2022 - frontiersin.org
Inflammatory immune response is apparently one of the determinants of progressive
exacerbation of valvular atrial fibrillation (VAF). Ferroptosis, an iron-dependent modality of …

[HTML][HTML] Exploration of immune infiltration and feature genes in viral hepatitis-associated liver fibrosis using transcriptome data

J Pan, Y Tian, F Hu, J Xu, N Tan, Y Han… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Immune cells play an essential role in virus-induced liver fibrosis. However, the
underlying mechanisms remain unclear. In this study, we systematically explored immune …

Alterations in peripheral T‐and B‐cell subsets in patients with systemic sclerosis

J Wu, X Zhang, S Lin, Q Wei, Z Lin… - International Journal of …, 2024 - Wiley Online Library
Objectives To determine the alteration of peripheral T and B cell subsets in patients with
systemic sclerosis (SSc) and to evaluate their correlation with the progression of SSc …

[HTML][HTML] Current Update on the Role of Inflammation in the Pathogenesis of SSc

D Elvira, R Masri - 2023 - intechopen.com
Systemic sclerosis (SSc), also known as scleroderma, is a systemic autoimmune rheumatic
disease characterized by dysregulation of the immune system, fibrosis of the skin and …

Paeoniflorin improves autoimmune myocarditis in young rat by inhibiting CXCR5 to reduce follicular helper T cells

C Wang, L Wang, L Wang - Autoimmunity, 2022 - Taylor & Francis
In the current study, we aimed to investigate the effect of paeoniflorin on autoimmune
myocarditis. A total of 72 young Lewis rats were randomly divided into control, experimental …

[HTML][HTML] The relationship between peripheral T follicular helper cells and disease severity in systemic sclerosis

M Sahinoglu, G Sargin, I Yavasoglu… - Clinical and Experimental …, 2024 - Springer
We aimed to investigate the association between follicular T helper cells (Tfh) and disease
severity in systemic sclerosis (SSc), a chronic connective tissue disease characterized by …

[HTML][HTML] Features of Peripheral Blood Th-Cell Subset Composition and Serum Cytokine Level in Patients with Activity-Driven Ankylosing Spondylitis

PA Shesternya, AA Savchenko, OD Gritsenko… - Pharmaceuticals, 2022 - mdpi.com
Th cells may exhibit pathological activity depending on the regulatory and functional signals
sensed under a wide range of immunopathological conditions, including ankylosing …

[HTML][HTML] 慢性移植物抗宿主病患者免疫细胞亚群分选的表面标志组合策略

杜雨軒, 王平, 葛晓军, 王筱淇, 洪涛, 王蔚浩, 何云地… - 2021 - aammt.tmmu.edu.cn
目的观测慢性移植物抗宿主病(chronic graft-versus-host disease, cGVHD)
患者免疫细胞亚群分布变化规律, 探讨免疫细胞表面标志物分选出的特定细胞亚群在cGVHD …