[HTML][HTML] Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …

The association of periodontal diseases with metabolic syndrome and obesity

S Jepsen, J Suvan, J Deschner - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a multifactorial chronic inflammatory disease associated with dysbiotic
plaque biofilms and characterized by progressive destruction of the tooth‐supporting …

Association between metabolic syndrome and periodontitis: The role of lipids, inflammatory cytokines, altered host response, and the microbiome

FQ Pirih, S Monajemzadeh, N Singh… - Periodontology …, 2021 - Wiley Online Library
Periodontitis has been associated with many systemic diseases and conditions, including
metabolic syndrome. Metabolic syndrome is a cluster of conditions that occur concomitantly …

Update on the pathogenesis and treatment of skeletal fragility in type 2 diabetes mellitus

S Khosla, P Samakkarnthai, DG Monroe… - Nature Reviews …, 2021 - nature.com
Fracture risk is increased in patients with type 2 diabetes mellitus (T2DM). In addition, these
patients sustain fractures despite having higher levels of areal bone mineral density, as …

Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations

JM Albandar, C Susin… - Journal of clinical …, 2018 - Wiley Online Library
Objectives This review proposes case definitions and diagnostic considerations of systemic
disorders and conditions that affect the periodontal attachment apparatus. Importance …

The impact of diabetes on periodontal diseases

DT Graves, Z Ding, Y Yang - Periodontology 2000, 2020 - Wiley Online Library
The susceptibility and severity of periodontal diseases is made more severe by diabetes,
with the impact on the disease process inversely proportional to the level of glycemic control …

The oral microbiota is modified by systemic diseases

DT Graves, JD Corrêa, TA Silva - Journal of dental research, 2019 - journals.sagepub.com
Periodontal diseases are initiated by bacteria that accumulate in a biofilm on the tooth
surface and affect the adjacent periodontal tissue. Systemic diseases such as diabetes …

[HTML][HTML] Evaluating all potential oral complications of diabetes mellitus

MJL Verhulst, BG Loos, VEA Gerdes… - Frontiers in …, 2019 - frontiersin.org
Diabetes mellitus (DM) is associated with several microvascular and macrovascular
complications, such as retinopathy, nephropathy, neuropathy, and cardiovascular diseases …

An update on the evidence for pathogenic mechanisms that may link periodontitis and diabetes

D Polak, L Shapira - Journal of clinical periodontology, 2018 - Wiley Online Library
Aim To provide an update of the review by Taylor (Journal of Clinical Periodontology, 2013,
40, S113) regarding the scientific evidence of the biological association between …

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils

C Engblom, C Pfirschke, R Zilionis, J Da Silva Martins… - Science, 2017 - science.org
INTRODUCTION Myeloid cells have emerged as key regulators of cancer growth because of
their abundance in the tumor stroma in a broad range of cancers, their association with …