[HTML][HTML] Silica nanoparticles: Biomedical applications and toxicity

Y Huang, P Li, R Zhao, L Zhao, J Liu, S Peng… - Biomedicine & …, 2022 - Elsevier
Silica nanoparticles (SiNPs) are composed of silicon dioxide, the most abundant compound
on Earth, and are used widely in many applications including the food industry, synthetic …

[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation

A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers

TI Janjua, Y Cao, F Kleitz, M Linden, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

Biodegradable metal–organic‐framework‐gated organosilica for tumor‐microenvironment‐unlocked glutathione‐depletion‐enhanced synergistic therapy

Y Ma, Z Su, L Zhou, L He, Z Hou, J Zou… - Advanced …, 2022 - Wiley Online Library
The clinical employment of cisplatin (cis‐diamminedichloroplatinum (II)(CDDP)) is largely
constrained due to the non‐specific delivery and resultant serious systemic toxicity. Small …

Harnessing inhaled nanoparticles to overcome the pulmonary barrier for respiratory disease therapy

Z Jin, Q Gao, K Wu, J Ouyang, W Guo… - Advanced Drug Delivery …, 2023 - Elsevier
The lack of effective treatments for pulmonary diseases presents a significant global health
burden, primarily due to the challenges posed by the pulmonary barrier that hinders drug …

Chitosan–Biotin-Conjugated PH-Responsive Ru (II) Glucose Nanogel: A Dual Pathway of Targeting Cancer Cells and Self-Drug Delivery

Pragti, BK Kundu, S Singh… - … Applied Materials & …, 2023 - ACS Publications
The current study paves the way for improved chemotherapy by creating pH-responsive
nanogels (NGs)(GC1 and GC2) loaded with synthetic ruthenium (II) arene complexes to …

Prospects and hazards of silica nanoparticles: Biological impacts and implicated mechanisms

R Ding, Y Li, Y Yu, Z Sun, J Duan - Biotechnology Advances, 2023 - Elsevier
With the thrive of nanotechnology, silica nanoparticles (SiNPs) have been extensively
adopted in the agriculture, food, cosmetic, and even biomedical industries. Due to the mass …

[HTML][HTML] Micro and nano-carriers-based pulmonary drug delivery system: Their current updates, challenges, and limitations–A review

M Kumar, AR Hilles, SHA Almurisi, A Bhatia… - JCIS Open, 2023 - Elsevier
The lung is an attractive target for drug delivery because of the ease of non-invasive
administration via inhalation, bypassing metabolism in the liver, direct delivery to the …

Inhaled lipid nanoparticles alleviate established pulmonary fibrosis

D Li, A Zhao, J Zhu, C Wang, J Shen, Z Zheng, F Pan… - Small, 2023 - Wiley Online Library
Pulmonary fibrosis, a sequela of lung injury resulting from severe infection such as severe
acute respiratory syndrome‐like coronavirus (SARS‐CoV‐2) infection, is a kind of life …

Delivery of curcumin by fucoidan-coated mesoporous silica nanoparticles: Fabrication, characterization, and in vitro release performance

X Zhang, Y Zhu, L Fan, J Ling, LY Yang, N Wang… - International Journal of …, 2022 - Elsevier
Mesoporous silica nanoparticles (MSN) are effective drug delivery carriers because of their
adjustable large pore size and high porosity. In this study, complex nanoparticles containing …