Cardiotoxicity of anticancer drugs: Molecular mechanisms and strategies for cardioprotection

MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …

Nanotechnology Approaches for Prevention and Treatment of Chemotherapy‐Induced Neurotoxicity, Neuropathy, and Cardiomyopathy in Breast and Ovarian Cancer …

S Nevins, CD McLoughlin, A Oliveros, JB Stein… - Small, 2023 - Wiley Online Library
Nanotechnology has emerged as a promising approach for the targeted delivery of
therapeutic agents while improving their efficacy and safety. As a result, nanomaterial …

Antineoplastic drugs inducing cardiac and vascular toxicity–An update

S Barachini, S Ghelardoni, ZV Varga, RA Mehanna… - Vascular …, 2023 - Elsevier
With the improvement in cancer prognosis due to advances in antitumor therapeutic
protocols and new targeted and immunotherapies, we are witnessing a growing increase in …

Management of fluoropyrimidine-induced cardiac adverse outcomes following cancer treatment

M Rajaeinejad, P Parhizkar-Roudsari… - Cardiovascular …, 2024 - Springer
Advancements in cancer treatments have improved survival rates but have also led to
increased cardiotoxicities, which can cause adverse cardiovascular events or worsen pre …

The effect of chlorogenic acid on 5-fluorouracil-induced oxidative damage in rat ovarian tissue

A Mentese, S Demir, N Türkmen, Y Aliyazıcıoğlu… - Farabi Tıp …, 2022 - dergipark.org.tr
5-fluorouracil (5-FU) is a potent anticancer agent, but its significant tissue toxicity associated
with increased oxidative stress and inflammation may limit its clinical use. Chlorogenic acid …

[HTML][HTML] Fluoropyrimidine-induced hand-foot syndrome and cardiotoxicity: recommendations for the use of the oral fluoropyrimidine S-1 in metastatic colorectal cancer

CJA Punt, V Heinemann, T Maughan, C Cremolini… - ESMO open, 2023 - Elsevier
Background Fluoropyrimidines (FPs) are an essential part of the majority of systemic
regimens in the treatment of metastatic colorectal cancer (CRC). The use of the oral FP S-1 …

Case report: Acute toxic myocardial damage caused by 5-fluorouracil—from enigma to success

R Lasica, J Spasic, L Djukanovic… - Frontiers in …, 2022 - frontiersin.org
Considering the pandemic of both cardiovascular diseases and oncological diseases, there
is an increasing need for the use of chemotherapy, which through various …

Cancer-Induced Resting Sinus Tachycardia: An Overlooked Clinical Diagnosis

M Sakellakis, J Reet, M Kladas, G Hoge… - Oncology …, 2024 - frontiersin.org
Elevated resting heart rate is frequently observed in cancer patients, and is associated with
increased mortality. Although specific chemotherapeutic agents can induce cardiotoxicity …

Cardiotoxicity of Anticancer Drugs: Molecular Mechanisms, Clinical Management and Innovative Treatment

F Gao, T Xu, F Zang, Y Luo, D Pan - Drug Design, Development …, 2024 - Taylor & Francis
With the continuous refinement of therapeutic measures, the survival rate of tumor patients
has been improving year by year, while cardiovascular complications related to cancer …

Predicting cardiovascular events with fluoropyrimidine chemotherapy using a standard cardiovascular risk calculator

A Abiodun, M Shawe‐Taylor, S Tyebally… - ESC Heart …, 2024 - Wiley Online Library
Aims Fluoropyrimidine chemotherapy is important for treatment of many solid tumours but is
associated with cardiotoxicity. The relationship of fluoropyrimidine‐associated cardiotoxicity …