Background Antimicrobial agents are effective weapons against foodborne pathogens;
however, antimicrobial resistance (AMR) is increasing globally. The bacterial cell envelope …

Covering: 1993 to the end of 2022As the rapid development of antibiotic resistance shrinks
the number of clinically available antibiotics, there is an urgent need for novel options to fill …

Membrane active peptides are known to porate lipid bilayers, but their exact
permeabilization mechanism and the structure of the nanoaggregates they form in …

Staphylococcus pseudintermedius is an opportunistic pathogen commonly found in canines,
and has garnered escalating interest due to its potential for zoonotic transmission and …

Helicobacter pylori is the primary cause of gastric adenocarcinoma, which afflicts more than
half of the world's population and seriously affects human health. However, achieving …

Cationic amphipathic antimicrobial agents inspired by antimicrobial peptides (AMPs) have
shown potential in combating multidrug-resistant bacteria because of minimal resistance …

Antimicrobial peptides (AMPs) are presented as potential scaffolds for antibiotic
development due to their desirable qualities including broad-spectrum activity, rapid action …

Antimicrobial peptides (AMPs) are promising candidates in combating multidrug-resistant
microorganisms because of their unique mode of action. Among these peptides, ultrashort …

Introduction Modern drug discovery revolves around designing ligands that target the
chosen biomolecule, typically proteins. For this, the evaluation of affinities of putative ligands …

Stereoscopic imaging of single molecules at the plasma membrane of single cell requires
spatial resolutions in 3 dimensions (xyz) at 10-nm level, which is rarely achieved using most …