Impact of cadmium mediated by tobacco use in musculoskeletal diseases

J Fernández-Torres, Y Zamudio-Cuevas… - Biological trace element …, 2022 - Springer
Tobacco use has a negative impact on health due to its relationship with the development of
high-mortality diseases, such as pulmonary cancer. However, the effect of cadmium (Cd) …

Emerging aspects of molecular biomarkers for diagnosis, prognosis and treatment response in rheumatoid arthritis

A Marquez, J Martin, FD Carmona - Expert review of molecular …, 2016 - Taylor & Francis
Important advances have occurred during the last decade in the understanding of the
pathogenesis of rheumatoid arthritis (RA). However, we are still far from having a clear …

Epigenetic changes: the missing link

D Kyburz, E Karouzakis, C Ospelt - Best Practice & Research Clinical …, 2014 - Elsevier
The association of rheumatoid arthritis (RA) with a number of genetic risk loci is well
established; however, only part of the risk to develop the disease is based on genetics …

[PDF][PDF] The role of nicotinamide adenine dinucleotide in the pathogenesis of rheumatoid arthritis: potential implications for treatment

W Chen, C Yi, L Jin - EMJ, 2018 - emjreviews.com
Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory, autoimmune disease
characterised by small joint swelling, deformity, and dysfunction. Its exact aetiology is …

Rheumatoid arthritis and epigenetics

K Klein, E Karouzakis, S Gay - The Epigenetics of Autoimmunity, 2018 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints, which leads to
cartilage damage, bone erosion, and subsequent joint deformation and loss of function …

Synovial fibroblasts: Main players in rheumatoid arthritis

K Klein, RE Gay, S Gay - Zeitschrift für Rheumatologie, 2016 - Springer
Rheumatoide Arthritis (RA) ist eine Autoimmunerkrankung, die durch eine chronische
Entzündung sowie die Degeneration der Gelenke bis hin zu deren fortwährenden …

Cadmium the missing link between smoking and increased rheumatoid disease activity?

M Cates, D Hutchinson - Annals of the Rheumatic Diseases, 2015 - ard.bmj.com
Ospelt et al 1 have observed a number of important and interesting observations in their
paper “Smoking induces transcription of the heat shock protein system in the joints”. It was …

Studies on the perturbations of CD4+ T cells function by cigarette smoke.

A Alghamdi - 2023 - etheses.bham.ac.uk
Background: A number of genes including HLA-DRB1 and variants of PTPN22 (which codes
for Lyp phosphatase) are associated with the development of rheumatoid arthritis (RA) …

Expression profile of long non coding RNA PVT1 in patients with ulcerative colitis

SE Ayoup - Egyptian Journal of Medical Microbiology, 2021 - journals.ekb.eg
Background: Ulcerative colitis (UC) is a chronic progressive inflammatory bowel disease,
many long non coding RNA (lncRNAs) have been studied to have a role in the pathogenesis …

Development and characterisation of phage display-derived antibodies for synovial specific drug delivery in Rheumatoid Arthritis

S Pagani - 2023 - qmro.qmul.ac.uk
OBJECTIVE: Rheumatoid Arthritis (RA) is a systemic autoimmune disease with a prevalence
of 0.5-1% worldwide. In the last two decades we observed the rapid evolution of RA …