Design and development of a self-assembling protein nanoparticle displaying PfHAP2 antigenic determinants recognized by natural acquired antibodies

F Zahedi, A Abouie Mehrizi, S Sardari, I Alemzadeh - PloS one, 2022 - journals.plos.org
Backgrounds In order to move towards the elimination and eradication of malaria in the
world, the development of vaccines is inevitable. Many modern vaccines are based on …

Cd loop fusion enhances the immunogenicity and the potential transmission blocking activity of Plasmodium falciparum Generative Cell Specific 1 (GCS1) antigen

L Nourani, MA Meigouni, S Afzali, M Zargar… - Biochemical and …, 2024 - Elsevier
Highlights•The potential ability of cd loop fusion (cd-HAP) to upsurge humoral and cellular
immune responses•The intensified Th1-directed immune responses in group received cd …

Optimized Refolding Buffers Oriented Humoral Immune Responses Versus PfGCS1 Self-Assembled Peptide Nanoparticle

L Nourani, A Lotfi, H Vand-Rajabpour… - Molecular …, 2024 - Springer
Developing a novel class of vaccine is pivotal for eliminating and eradicating malaria.
Preceding investigations demonstrated partial blocking activity in malaria transmission …

MAM7 from Vibrio parahaemolyticus: Expression, Purification and Effects on RAW264. 7 cells

Q Zeng, P Lai, M Huang, X Peng, J Huang… - Protein Expression and …, 2024 - Elsevier
V parahaemolyticus is a Gram-negative bacterium that causes gastroenteritis. Within the
realm of bacterial interactions with the gut, the outer membrane protein MAM7 plays a key …

Optimizing recombinant antibody fragment production: A comparison of artificial intelligence and statistical modeling

M Basafa, A Hashemi… - Biotechnology and Applied …, 2024 - Wiley Online Library
Maximizing the recombinant protein yield necessitates optimizing the production medium.
This can be done using a variety of methods, including the conventional “one‐factor‐at‐a …

Implementación de una plataforma phage display para la producción de anticuerpos recombinantes anti-NAD+ quinasa de Plasmodium falciparum (PfNADK)

MÁ Melo Chinchilla - repositorio.unal.edu.co
La tecnología phage display permite la generación de librerías de anticuerpos
monoclonales para su uso en investigación, diagnóstico y terapia. En este estudio, se …