HIV tissue reservoirs: current advances in research

K Li, B Liu, R Ma, Q Zhang - AIDS patient care and STDs, 2023 - liebertpub.com
Acquired immunodeficiency syndrome (AIDS), caused by the human immunodeficiency
virus (HIV), has become a heavy burden of disease and an important public health problem …

[HTML][HTML] Pillars of long-term antiretroviral therapy success

L Taramasso, M Andreoni, A Antinori, A Bandera… - Pharmacological …, 2023 - Elsevier
Background Meeting the challenge of antiretroviral therapy (ART) whose efficacy can last a
lifetime requires continuous updating of the virological, pharmacological, and quality of life …

Prevalence of HIV-1 drug resistance mutations in proviral DNA in the Swiss HIV Cohort Study, a retrospective study from 1995 to 2018

B Jaha, CD Schenkel, L Jörimann… - Journal of …, 2023 - academic.oup.com
Background Genotypic resistance testing (GRT) is routinely performed upon diagnosis of
HIV-1 infection or during virological failure using plasma viral RNA. An alternative source for …

[HTML][HTML] Temporal trend of drug-resistance and APOBEC editing in PBMC genotypic resistance tests from HIV-1 infected virologically suppressed individuals

D Armenia, R Gagliardini, C Alteri, V Svicher… - Journal of Clinical …, 2023 - Elsevier
Background We aimed at evaluating the temporal trend of drug-resistance and APOBEC
editing from HIV-DNA genotypic resistance tests (GRT) in virologically suppressed …

[PDF][PDF] Pathology of HIV/AIDS

EC Klatt - The Mercer University of Medicine Savannah, 2017 - webpath.med.utah.edu
The human immunodeficiency virus (HIV) was unknown until the early 1980's when
increasing numbers of cases of unusual opportunistic infections and Kaposi sarcoma in …

[HTML][HTML] Assessing the virologic impact of archived resistance in the dolutegravir/lamivudine 2-drug regimen HIV-1 switch study TANGO through week 144

R Wang, J Wright, P Saggu, M Ait-Khaled, R Moodley… - Viruses, 2023 - mdpi.com
The TANGO study (ClinicalTrials. gov, NCT03446573) demonstrated that switching to
dolutegravir/lamivudine (DTG/3TC) was non-inferior to continuing tenofovir alafenamide …

HIV drug resistance

C Chu, L Pollock, RW Shafer - Fundamentals of HIV Medicine …, 2023 - books.google.com
Approximately 35% of persons with diagnosed HIV infection in the United States do not have
a suppressed viral load (Centers for Disease Control and Prevention, 2022), underscoring …

Evaluation of archived drug resistance mutations in HIV‐1 DNA among vertically infected adolescents under antiretroviral treatment in Cameroon: Findings during the …

AC Ka'e, J Fokam, WLR Togna Pabo, A Nanfack… - HIV …, 2023 - Wiley Online Library
Background With the success of antiretroviral therapy (ART), children born with HIV are
more likely to reach adolescence. However, frequent non‐adherence to ART in adolescents …

Long-acting cabotegravir/rilpivirine for HIV-1 treatment: real-world evaluation of barriers to implementation

BR Wood, SG Kassaye, J Gerstoft - AIDS, 2023 - journals.lww.com
Availability of long-acting, injectable (LAI) cabotegravir/rilpivirine (CAB/RPV) was eagerly
anticipated, but uptake remains sluggish. Most clinics have encountered numerous hurdles …

Comparison of HIV-1 DNA load measurements in blood and in relation to successful proviral sequencing

A Fuchs, A Wasser, C Faua, S Caspar, F Jegou… - Infectious Diseases …, 2024 - Elsevier
Objective HIV DNA sequencing is now routinely used for HIV-infected individuals on
antiretroviral therapy (ART) with or without partial genotypic history. Successful amplification …