Brain glucose metabolism: integration of energetics with function
GA Dienel - Physiological reviews, 2019 - journals.physiology.org
Glucose is the long-established, obligatory fuel for brain that fulfills many critical functions,
including ATP production, oxidative stress management, and synthesis of neurotransmitters …
including ATP production, oxidative stress management, and synthesis of neurotransmitters …
Integration of GC–MS and LC–MS for untargeted metabolomics profiling
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …
scientific community as it is applied in several researches relating to diseases diagnosis …
Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention
YAR Mahaman, KS Embaye, F Huang, L Li, F Zhu… - Ageing research …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), being the number one in terms of dementia burden, is an
insidious age-related neurodegenerative disease and is presently considered a global …
insidious age-related neurodegenerative disease and is presently considered a global …
Glutamate and GABA in microglia-neuron cross-talk in Alzheimer's disease
GA Czapski, JB Strosznajder - International Journal of Molecular Sciences, 2021 - mdpi.com
The physiological balance between excitation and inhibition in the brain is significantly
affected in Alzheimer's disease (AD). Several neuroactive compounds and their signaling …
affected in Alzheimer's disease (AD). Several neuroactive compounds and their signaling …
Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence
Alzheimer's disease (AD) is characterized by non-linear, genetic-driven pathophysiological
dynamics with high heterogeneity in biological alterations and disease spatial-temporal …
dynamics with high heterogeneity in biological alterations and disease spatial-temporal …
Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: relationship to neuroimaging and CSF biomarkers
K Nho, A Kueider-Paisley… - Alzheimer's & …, 2019 - Elsevier
Abstract Introduction Bile acids (BAs) are the end products of cholesterol metabolism
produced by human and gut microbiome co-metabolism. Recent evidence suggests gut …
produced by human and gut microbiome co-metabolism. Recent evidence suggests gut …
[HTML][HTML] Anti-oxidant and anti-inflammatory activity of ketogenic diet: new perspectives for neuroprotection in Alzheimer's disease
A Pinto, A Bonucci, E Maggi, M Corsi, R Businaro - Antioxidants, 2018 - mdpi.com
The ketogenic diet, originally developed for the treatment of epilepsy in non-responder
children, is spreading to be used in the treatment of many diseases, including Alzheimer's …
children, is spreading to be used in the treatment of many diseases, including Alzheimer's …
Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease
Metabolites, the biochemical products of the cellular process, can be used to measure
alterations in biochemical pathways related to the pathogenesis of Alzheimer's disease …
alterations in biochemical pathways related to the pathogenesis of Alzheimer's disease …
[HTML][HTML] Phytochemicals and cognitive health: Are flavonoids doing the trick?
Flavonoids constitute a large group of polyphenolic compounds with numerous effects on
behaviour and cognition. These effects vary from learning and memory enhancement to an …
behaviour and cognition. These effects vary from learning and memory enhancement to an …
Current aspects of the endocannabinoid system and targeted THC and CBD phytocannabinoids as potential therapeutics for Parkinson's and Alzheimer's diseases: a …
Neurodegeneration leading to Parkinson's disease (PD) and Alzheimer's disease (AD) has
become a major health burden globally. Current treatments mainly target controlling …
become a major health burden globally. Current treatments mainly target controlling …