Wnt, a secreted glycoprotein, has an approximate molecular weight of 40 kDa, and it is a
cytokine involved in various biological phenomena including ontogeny, morphogenesis …

Epithelial-mesenchymal transition (EMT) is defined as a process in which differentiated
epithelial cells undergo phenotypic transformation into myofibroblasts capable of producing …

What we know about bone resorption has changed a lot in the last few decades. The
osteoclast is the only cell to nibble and break down the bone, and in the formation and …

High-grade serous ovarian cancer (HGSOC) is an aggressive malignancy often diagnosed
at an advanced stage. Although most HGSOC patients respond initially to debulking surgery …

STARD1 moves cholesterol (CHOL) from the outer mitochondrial membrane (OMM) to the
inner membrane (IMM) in steroidogenic cells. This activity is integrated into CHOL trafficking …

Salt-inducible kinases (SIKs) are calcium/calmodulin-dependent protein kinase (CAMK)-like
(CAMKL) family members implicated in insulin signal transduction, metabolic regulation …

Background Acute kidney injury (AKI), with a high morbidity and mortality, is recognized as a
risk factor for chronic kidney disease (CKD). AKI-CKD transition has been regarded as one …

Salt inducible kinase 2 (SIK2) is a calcium/calmodulin-dependent protein kinase-like kinase
that is implicated in a variety of biological phenomena, including cellular metabolism …

The kinase domain is highly conserved among protein kinases' in terms of both sequence
and structure. Conformational rearrangements of the kinase domain are affected by the …

Damage to kidney cells can occur due to a variety of ischemic and toxic insults and leads to
inflammation and cell death, which can result in acute kidney injury (AKI). Inflammation plays …