The Role of One-Carbon Metabolism and Methyl Donors in Medically Assisted Reproduction: A Narrative Review of the Literature

K Sfakianoudis, A Zikopoulos, S Grigoriadis… - International Journal of …, 2024 - mdpi.com
One-carbon (1-C) metabolic deficiency impairs homeostasis, driving disease development,
including infertility. It is of importance to summarize the current evidence regarding the …

[HTML][HTML] Morphokinetics of In Vitro-Derived Embryos—A Lesson from Human and Bovine Studies

S Yaacobi-Artzi, D Kalo, Z Roth - Dairy, 2024 - mdpi.com
Embryo transfer has become a major method to improve fertility in both humans and cattle.
The current review focuses on predicting an embryo with a high developmental competence …

Metabolic imaging of human embryos is predictive of ploidy status but is not associated with clinical pregnancy outcomes: a pilot trial

D Sakkas, C Gulliford, G Ardestani, O Ocali… - Human …, 2024 - academic.oup.com
STUDY QUESTION Does fluorescence lifetime imaging microscopy (FLIM)-based metabolic
imaging assessment of human blastocysts prior to frozen transfer correlate with pregnancy …

Culture systems for the human embryo

DK Gardner, M Lane - Textbook of assisted reproductive …, 2017 - taylorfrancis.com
INTRODUCTION Embryo culture is frequently mistaken for a relatively simple procedure. In
reality, it is a complex task, requiring proactive quality control and quality assurance …

Basal FSH values are positively associated with aneuploidy incidence in pre-advanced maternal age (AMA) but not in AMA patients

CK Jacobs, M Nicolielo, JR Alegretti, MD Canto… - Journal of Assisted …, 2024 - Springer
Purpose To assess the impact of maternal age on the association between maternal basal
FSH and aneuploidy. Methods A retrospective study including data from 1749 blastocysts …

[HTML][HTML] Professional MHSc in Laboratory Medicine; Training clinical laboratory scientists in an integrated program at a research-intensive university.

AI Gotlieb, FI Lu, W Tsui, H Shapiro, TJ Brown… - The American Journal of …, 2024 - Elsevier
A two-year professional MHSc program at the University of Toronto provides a unique
integrated educational program to train allied health science personnel to practice as …

Professional Master of Health Science in Laboratory Medicine: Training Clinical Laboratory Scientists in an Integrated Program at a Research-Intensive University

AI Gotlieb, FI Lu, W Tsui, H Shapiro… - The American Journal …, 2024 - ajp.amjpathol.org
A 2-year professional master of health science program at the University of Toronto provides
a unique integrated educational program to train allied health science personnel to practice …

The ovarian stimulation regimen does not affect aneuploidy or blastocyst rate

M Cozzolino, L Mossetti, G Mariani, D Galliano… - Reproductive …, 2024 - Elsevier
Research question Could the total dose (< 3000 IU or≥ 3000 IU) and type of exogenous
gonadotrophin (ie recombinant FSH and/or human menopausal gonadotrophin [HMG]) …

[HTML][HTML] Genome-wide analyses identify 21 infertility loci and over 400 reproductive hormone loci across the allele frequency spectrum

SS Venkatesh, LBL Wittemans, DS Palmer, NA Baya… - medRxiv, 2024 - ncbi.nlm.nih.gov
Genome-wide association studies (GWASs) may help inform treatments for infertility, whose
causes remain unknown in many cases. Here we present GWAS meta-analyses across six …

The human embryo selection arena is associated with transposable element activity

A Osnato, V Pasque, L David - PLoS Biology, 2023 - journals.plos.org
The human embryo selection arena is associated with transposable element activity | PLOS
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