[HTML][HTML] Lycopene in the prevention of cardiovascular diseases

S Przybylska, G Tokarczyk - International Journal of Molecular Sciences, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide.
Oxidative stress and inflammation are pathophysiological processes involved in the …

[HTML][HTML] Mitochondrial dysfunction: the hidden player in the pathogenesis of atherosclerosis?

G Ciccarelli, S Conte, G Cimmino, P Maiorano… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is a multifactorial inflammatory pathology that involves metabolic processes.
Improvements in therapy have drastically reduced the prognosis of cardiovascular disease …

[HTML][HTML] Inflammatory mechanisms of diabetes and its vascular complications

LV Nedosugova, YV Markina, LA Bochkareva… - Biomedicines, 2022 - mdpi.com
The main cause of death in patients with type 2 DM is cardiovascular complications resulting
from the progression of atherosclerosis. The pathophysiology of the association between …

[HTML][HTML] Endothelial cell phenotype, a major determinant of venous thrombo-inflammation

M Pilard, EL Ollivier, V Gourdou-Latyszenok… - Frontiers in …, 2022 - frontiersin.org
Reduced blood flow velocity in the vein triggers inflammation and is associated with the
release into the extracellular space of alarmins or damage-associated molecular patterns …

[HTML][HTML] Mitochondrial dysfunction in vascular wall cells and its role in atherosclerosis

D Salnikova, V Orekhova, A Grechko… - International Journal of …, 2021 - mdpi.com
Altered mitochondrial function is currently recognized as an important factor in
atherosclerosis initiation and progression. Mitochondrial dysfunction can be caused by …

[HTML][HTML] Mitophagy in atherosclerosis: from mechanism to therapy

Y Zhang, J Weng, L Huan, S Sheng, F Xu - Frontiers in Immunology, 2023 - frontiersin.org
Mitophagy is a type of autophagy that can selectively eliminate damaged and depolarized
mitochondria to maintain mitochondrial activity and cellular homeostasis. Several pathways …

[HTML][HTML] Novel insights and current evidence for mechanisms of atherosclerosis: mitochondrial dynamics as a potential therapeutic target

D Li, S Yang, Y Xing, L Pan, R Zhao, Y Zhao… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular disease (CVD) is the main cause of death worldwide. Atherosclerosis is the
underlying pathological basis of CVD. Mitochondrial homeostasis is maintained through the …

The Synergistic Effect of Ginkgo biloba Extract 50 and Aspirin Against Platelet Aggregation

J Ke, MT Li, YJ Huo, YQ Cheng, SF Guo… - Drug Design …, 2021 - Taylor & Francis
Purpose We aimed to investigate potential synergistic antiplatelet effects of Ginkgo biloba
extract (GBE50) in combination with aspirin using in vitro models. Methods Arachidonic acid …

[HTML][HTML] Role of mitochondrial DNA copy number in incident cardiovascular diseases and the association between cardiovascular disease and type 2 diabetes: A …

K Sundquist, J Sundquist, K Palmer, AA Memon - Atherosclerosis, 2022 - Elsevier
Background and aims Mitochondrial DNA copy number (mtDNA-CN) is a surrogate
biomarker of mitochondrial dysfunction and is associated with type 2 diabetes (T2D) and …

[HTML][HTML] Pyroptosis in NLRP3 inflammasome-related atherosclerosis

X Zeng, D Liu, X Huo, Y Wu, C Liu, Q Sun - Cell Stress, 2022 - ncbi.nlm.nih.gov
Pyroptosis is a proinflammatory form of programmed cell death in response to inflammation.
It involves in the pathogenesis and outcomes of atherosclerosis characterized by NLRP3 …