Advances in hiPSC isolation and reprogramming and hPSC-CM differentiation have
prompted their therapeutic application and utilization for evaluating potential cardiovascular …

The rapid dissemination of SARS-CoV-2 has made COVID-19 a tremendous social,
economic, and health burden. Despite the efforts to understand the virus and treat the …

The bidomain equations form the state-of-the-art model of cardiac electrophysiology and
describe normal or pathological propagation of the excitation wave through cardiac tissue. If …

Background: Antiarrhythmic drugs are the first-line treatment for atrial fibrillation (AF), but
their effect is highly dependent on the characteristics of the patient. Moreover, anatomical …

Sudden cardiac arrest is a malfunction of the heart's electrical system, typically caused by
ventricular arrhythmias, that can lead to sudden cardiac death (SCD) within minutes …

Background A significant proportion of the world population suffer from cardiac arrythmia
that lead to arrest, sudden cardiac death, and often a severely reduced quality of life post …

With many advancements in in silico multiscale biology in recent years, the paramount
challenge is to translate the accumulated knowledge into exciting industry partnerships and …

[EN] Atrial Fibrillation (AF) is one of the most common arrhythmias in clinical practice and
thus far, the electrophysiological mechanisms underlying its initiation and maintenance are …

The paradigm of biological systems provides a framework to quantify the behavior of
biological processes. Mathematical modeling is one of the analytical tools of biological …

The paper deals with the transformation of a weakly nonlinear system of differential
equations in a special form into a simplified form and its relation to the normal form and …