Clove (Syzygium aromaticum) is one of the most valuable spices that has been used for
centuries as food preservative and for many medicinal purposes. Clove is native of …

With regard to the varied, nonculinary uses of hot pepper, there is apparently little new under
the sun. For example, Incas burned dried chili peppers to combat the invading Spaniards by …

Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The
discovery of efficient drugs that can relieve pain is a subject of research in the …

The capsaicin (vanilloid) receptor, TRPV1, is a heat-activated cation channel modulated by
inflammatory mediators and contributes to acute and chronic pain. TRPV1 channel is one of …

Clove is a common spice used as a flavorant and natural preservative in food industries due
to its rich phenolic constituents like eugenol and eugenol acetate etc. These phenolic …

Members of the transient receptor potential (TRP) family of nonselective cation channels are
involved in several pathological and physiological conditions. The search for the molecular …

There is considerable interest in developing topical microbicides; products to be used
intravaginally by women for protection against sexually transmitted diseases. Many …

The structural similarity of eugenol with capsaicin suggests that these two agents may share
molecular mechanisms to produce their effects. We investigated the effects of eugenol in …

Eugenol is the principle chemical constituent of clove oil and has been used to cure dental
problems for ages. Eugenol is an integral part of the dentist's kit due to its analgesic, local …

Neuropathic pain is a type of chronic pain following central or peripheral nervous system
lesions that cause allodynia (pain initiated by a non-painful stimulus) and hyperalgesia …