A critical review of nebivolol and its fixed-dose combinations in the treatment of hypertension

AFG Cicero, M Kuwabara, C Borghi - Drugs, 2018 - Springer
Abstract β-Adrenergic receptor blockers (β-blockers) are well-known useful and cost-
effective drugs for managing hypertensive patients with coronary heart disease, stroke, and …

Does nebivolol have renoprotective action in patients with chronic kidney disease conditions? An integrative review

JFA Encinas, CHF Peiro, MM Perez… - European Journal of …, 2021 - Elsevier
Systemic arterial hypertension (SAH) is a chronic disease of multifactorial origin and one of
the main risk factors for major adverse cardiovascular events (MACE), which are the leading …

Photochemical degradation of nebivolol in different natural organic matter solutions under simulated sunlight irradiation: Kinetics, mechanism and degradation …

J Wang, K Wang, Y Guo, J Niu - Water Research, 2020 - Elsevier
Nebivolol (NEB) is widely used for the treatment of hypertension and chronic heart failure
and has become an ubiquitous emerging organic pollutant. It has been shown to undergo …

Transcriptomics and protein biomarkers reveal the detoxifying mechanisms of UV radiation for nebivolol toward zebrafish (Danio rerio) embryos/larvae

Y He, R Zhu, Y Cai, Y Zhang, Y Zhang, S Pan… - Aquatic toxicology, 2022 - Elsevier
Abstract Nebivolol (NEB), a β-blocker frequently used to treat cardiovascular diseases, has
been widely detected in aquatic environments, and can be degraded under exposure to UV …

Nebivolol ameliorated kidney damage in Zucker diabetic fatty rats by regulation of oxidative stress/NO pathway: Comparison with captopril

Y Wang, W An, F Zhang, M Niu, Y Liu… - Clinical and …, 2018 - Wiley Online Library
The aim was to evaluate the effects and mechanisms of nebivolol on renal damage in
Zucker diabetic fatty (ZDF) rats, in comparison with those of atenolol and captopril. Animals …

Nebivolol prevents ethanol-induced reactive oxygen species generation and lipoperoxidation in the rat kidney by regulating NADPH oxidase activation and …

GT do Vale, NA Gonzaga, JA Simplicio… - European Journal of …, 2017 - Elsevier
We studied whether the β 1-adrenergic antagonist nebivolol would prevent ethanol-induced
reactive oxygen species generation and lipoperoxidation in the rat renal cortex. Male Wistar …

[HTML][HTML] Ameliorative effect of nebivolol in doxorubicin-induced cardiotoxicity

H Al-Amir, A Janabi, NR Hadi - Journal of Medicine and Life, 2023 - ncbi.nlm.nih.gov
This study aimed to investigate the potential of nebivolol in preventing doxorubicin-induced
cardiotoxicity by targeting the inflammatory, oxidative, and apoptotic pathways. Twenty-eight …

Avaliação dos efeitos do Nebivolol sobre a nefrotoxicidade em ratos tratados com Tenofovir

MM Nascimento - 2023 - teses.usp.br
O tenofovir disoproxil fumarato (TDF), componente amplamente prescrito em regimes
antirretrovirais, tem sido associado à nefrotoxicidade. O nebivolol é um bloqueador seletivo …

Contrast-induced nephropathy: searching for new solutions to prevent its development

DD Ivanov - Почки, 2019 - cyberleninka.ru
Contrast-induced nephropathy (CIN) is the main cause of acute kidney injury and worsens
the prognosis of chronic kidney disease. To evaluate the clinical risk score of CIN …

[PDF][PDF] Treatment of Hypertension in the Different Stages of Chronic Kidney

ART Villanueva, CE Flores-Riva, JR Valdez - Hypertension, 2019 - scholar.archive.org
The blood pressure (BP) targets for patients with chronic kidney disease (CKD) to decrease
the risk of cardiovascular outcomes and progression of renal disease remain unclear. In …