Given the key roles of the cerebellum in motor, cognitive, and affective operations and given
the decline of brain functions with aging, cerebellar circuitry is attracting the attention of the …

The γ-aminobutyric acid (GABA) ergic system is the primary inhibitory neurotransmission
system in the mammalian brain. Its dysregulation has been shown in multiple brain …

Background: Recent studies have discovered that functional connections are impaired
among patients with Alzheimer's disease (AD), even at the preclinical stage. The cerebellum …

Alzheimer's disease (AD) is one of the most prevalent diseases that lead to memory
deficiencies, severe behavioral abnormalities, and ultimately death. The need for more …

The apolipoprotein‐E (APOE) ε4 allele is the greatest genetic risk factor for late‐onset
Alzheimer's disease (AD), but alone it is not sufficiently predictive. Because …

The notion that the cerebellum is devoted exclusively to motor control has been replaced by
a more sophisticated understanding of its role in neurological function, one that includes …

Simple Summary Modifications of gene expression (epigenetic alterations) have been
implicated in the pathogenesis of complex diseases, such as Alzheimer's disease (AD) …

Scientific theories on the functioning and dysfunction of the human brain require an
understanding of its development—before and after birth and through maturation to …

Gradient-based analyses have contributed to the description of cerebellar functional
neuroanatomy. More recently, functional gradients of the cerebellum have been used as a …

The cerebellum contributes to motor and higher-order control throughout
neurodevelopment, with marked growth during childhood. Few studies have investigated …