Autoimmunity refers to the phenomenon that the body's immune system produces antibodies
or sensitized lymphocytes to its own tissues to cause an immune response. Immune …

C1q is a crucial component of the complement system, which is activated through the
classical pathway to perform non-specific immune functions, serving as the first line of …

Background Macrophages are key innate immune cells implicated in the pathogenesis of
Behçet's disease (BD), and macrophage polarization plays a pivotal role in inflammatory …

Systemic sclerosis (SSc) is a complex disease that affects the connective tissue, causing
fibrosis. SSc patients show altered immune cell composition and activation in the peripheral …

To explore the molecular network mechanism of Celastrol in the treatment of rheumatoid
arthritis (RA) based on a novel strategy (integrated systems pharmacology, proteomics …

Background Sepsis is a life-threatening organ dysfunction caused by abnormal immune
responses to various, predominantly bacterial, infections. Different bacterial infections lead …

Uveitis is the most common form of ocular lesions in Behcet's disease, severely affecting
visual function. Molecular pathological changes of ocular lesions in patients with Behcet's …

Previous studies have reported that visfatin can regulate macrophage polarisation, which
has been demonstrated to participate in cardiac remodelling. The aims of this study were to …

Vasculogenic mimicry (VM) describes the ability of highly aggressive tumor cells to develop
pseudovascular structures without the participation of endothelial cells. PARP1 is implicated …

Introduction Peripheral monocytes in humans are conventionally divided into classical (CL,
CD14++ CD16−), intermediate (INT, CD14++ CD16+) and non-classical (NC, CD14dim …