Biological Activities and Secondary Metabolites from Sophora tonkinensis and Its Endophytic Fungi
JJ Liang, PP Zhang, W Zhang, D Song, X Wei, X Yin… - Molecules, 2022 - mdpi.com
The roots of Sophora tonkinensis Gagnep., a traditional Chinese medicine, is known as
Shan Dou Gen in the Miao ethnopharmacy. A large number of previous studies have …
Shan Dou Gen in the Miao ethnopharmacy. A large number of previous studies have …
Inhibition of Cytochrome P450 Activities by Sophora flavescens Extract and Its Prenylated Flavonoids in Human Liver Microsomes
D Yim, MJ Kim, Y Shin, SJ Lee… - Evidence‐based …, 2019 - Wiley Online Library
Sophora flavescens possesses several pharmacological properties and has been widely
used for the treatment of diarrhea, inflammation, abscess, dysentery, and fever in East Asian …
used for the treatment of diarrhea, inflammation, abscess, dysentery, and fever in East Asian …
Systematic analysis of chemical profiles of Sophorae tonkinensis Radix et Rhizoma in vitro and in vivo using UPLC‐Q‐TOF‐MSE
W Yuan, Z Huang, S Xiao, Y Zhang… - Biomedical …, 2022 - Wiley Online Library
Abstract Sophorae tonkinensis Radix et Rhizoma (S. tonkinensis) has been recorded as a
'poisonous' Chinese herbal medicine in Chinese Pharmacopoeia 2020. The clinical reaction …
'poisonous' Chinese herbal medicine in Chinese Pharmacopoeia 2020. The clinical reaction …
Pharmacokinetic characterization and bioavailability barrier for the key active components of botanical drug antitumor B (ATB) in mice for chemoprevention of oral …
This study aims to characterize the pharmacokinetic (PK) profiles and identify important
bioavailability barriers and pharmacological pathways of the key active components (KACs) …
bioavailability barriers and pharmacological pathways of the key active components (KACs) …
Lack of Correlation between In Vitro and In Vivo Studies on the Inhibitory Effects of (‒)-Sophoranone on CYP2C9 Is Attributable to Low Oral Absorption and Extensive …
YF Zheng, SH Bae, Z Huang, SU Chae, SJ Jo, HJ Shim… - Pharmaceutics, 2020 - mdpi.com
(‒)-Sophoranone (SPN) is a bioactive component of Sophora tonkinensis with various
pharmacological activities. This study aims to evaluate its in vitro and in vivo inhibitory …
pharmacological activities. This study aims to evaluate its in vitro and in vivo inhibitory …
Can the CEIBA cocktail designed for human cytochrome P450 enzymes be used in the rat for drug interaction studies?
P Magalhães, F De Andrés… - … of Pharmacy & …, 2016 - journals.library.ualberta.ca
Purpose-The CEIBA cocktail consisting of caffeine (CAF), omeprazole (OZ),
dextromethorphan (DM) and losartan (LOS) was previously proposed for the clinical …
dextromethorphan (DM) and losartan (LOS) was previously proposed for the clinical …
Characterization of alkaloids in radix Sophora tonkinensis by UPLC-Q-TOF-MS/MS and its application in the comparison of two different habitats
XX Zong, Y Wang, JL Xiong, YH Ping… - Natural Product …, 2021 - Taylor & Francis
Sophora tonkinensis is widely used as traditional Chinese medicine for treating the swelling
of the gums and tongue and mouth sores due to flame stomach fire. It is mainly origin from …
of the gums and tongue and mouth sores due to flame stomach fire. It is mainly origin from …
斑马鱼在中药毒性靶器官研究中的进展
张勇， 郭胜亚， 邓中平， 李春启 - 中国新药杂志, 2016 - cqvip.com
该文介绍了斑马鱼模型的特点及其在中药毒性靶器官研究中的应用, 重点介绍了在急性毒性,
肝脏毒性, 心血管毒性, 肾脏毒性和神经毒性研究等方面的应用, 系统分析了斑马鱼这一新型模式 …
肝脏毒性, 心血管毒性, 肾脏毒性和神经毒性研究等方面的应用, 系统分析了斑马鱼这一新型模式 …
Biopharmaceutical and Pharmacokinetic Studies of a Botanical Drug–Antitumor B–as a Chemopreventive Agent Against Oral Cancer
DT Bui - 2021 - uh-ir.tdl.org
Abstract Purpose and Specific Aims Antitumor B (ATB), also known as Zeng Sheng Ping, is a
Chinese herbal mixture composed of six plants and approved for use in China for dysplasia …
Chinese herbal mixture composed of six plants and approved for use in China for dysplasia …
Determination and pharmacokinetics of calycanthine in rat plasma by UPLC-MS/MS
M Lu, X Lu, Z Yu, C Wen - Acta Chromatographica, 2020 - akjournals.com
Calycanthine is an important class of alkaloids extracted and isolated from the roots, leaves,
flowers and fruits of Chimonanthus praecox. In this work, the UPLC-MS/MS method was …
flowers and fruits of Chimonanthus praecox. In this work, the UPLC-MS/MS method was …