Three-dimensional Spheroid Culture Enhances Multipotent Differentiation and Stemness Capacities of Human Dental Pulp‐derived Mesenchymal Stem Cells by …

YH Chan, YC Lee, CY Hung, PJ Yang, PC Lai… - Stem Cell Reviews and …, 2021 - Springer
Abstract Background Three-dimensional (3D) culture of mesenchymal stem cells has
become an important research and development topic. However, comprehensive analysis of …

[HTML][HTML] Priming strategies for controlling stem cell fate: applications and challenges in dental tissue regeneration

SY Zhang, JY Ren, B Yang - World Journal of Stem Cells, 2021 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSCs) have attracted intense interest in the field of dental
tissue regeneration. Dental tissue is a popular source of MSCs because MSCs can be …

Effect of ascorbic acid on differentiation, secretome and stemness of stem cells from human exfoliated deciduous tooth (SHEDs)

S Bhandi, A Alkahtani, M Mashyakhy… - Journal of Personalized …, 2021 - mdpi.com
Stem cells from human exfoliated deciduous teeth (SHEDs) are considered a type of
mesenchymal stem cells (MSCs) because of their unique origin from the neural crest …

Comparison of osteogenic potentials of dental pulp and bone marrow mesenchymal stem cells using the new cell transplantation platform, cellsaic, in a rat congenital …

J Lyu, Y Hashimoto, Y Honda, N Matsumoto - International Journal of …, 2021 - mdpi.com
Scaffolds stimulate cell proliferation and differentiation and play major roles in providing
growth and nutrition factors in the repair of bone defects. We used the recombinant peptide …

Biomimetic collagen-sodium alginate-titanium oxide (TiO2) 3D matrix supports differentiated periodontal ligament fibroblasts growth for periodontal tissue …

J Elango, PR Selvaganapathy, G Lazzari, B Bao… - International journal of …, 2020 - Elsevier
Fabrication of biomaterial that mimics a suitable biological microenvironment is still a major
challenge in the field of periodontitis treatment. Hence, in this report, we presented for the …

Novel mesenchymal stem cell spheroids with enhanced stem cell characteristics and bone regeneration ability

Y Ohori-Morita, K Niibe, P Limraksasin… - Stem cells …, 2022 - academic.oup.com
Mesenchymal stem cells (MSCs) exhibit self-renewal, multi-lineage differentiation potential
and immunomodulatory properties, and are promising candidates for cellular therapy of …

Xeno-free spheroids of human gingiva-derived progenitor cells for bone tissue engineering

S Shanbhag, S Suliman, AI Bolstad… - … in bioengineering and …, 2020 - frontiersin.org
Gingiva has been identified as a minimally invasive source of multipotent progenitor cells
(GPCs) for use in bone tissue engineering (BTE). To facilitate clinical translation, it is …

In vitro characterization of dental pulp stem cells cultured in two microsphere-forming culture plates

NU Bu, HS Lee, BN Lee, YC Hwang, SY Kim… - Journal of Clinical …, 2020 - mdpi.com
Various three-dimensional (3D) culture methods have been introduced to overcome the
limitations of in vitro culture and mimic in vivo conditions. This study aimed to evaluate two …

A comprehensive analysis of human dental pulp cell spheroids in a three-dimensional pellet culture system

S Zhang, P Buttler-Buecher, B Denecke… - Archives of Oral …, 2018 - Elsevier
Abstract Objective Three-dimensional (3D) cell culture methods are of high importance to
studies of biological processes. This is particularly the case with spheroid cultures, which …

Cellular senescence in craniofacial tissue regeneration: inducers, biomarkers, and interventions

W Tang, F Huo, J Long, S Zhang… - Tissue Engineering Part B …, 2024 - liebertpub.com
Craniofacial defects and dental tissue loss have significant negative impacts on the structure
and function of jaws and face, often resulting in psychological issues in patients …