Advances in understanding the pathogenesis of HLH

GN Usmani, BA Woda… - British journal of …, 2013 - Wiley Online Library
Haemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory disorder resulting from
immune dysfunction reflecting either primary immune deficiency or acquired failure of …

Cytogenetics of pediatric acute myeloid leukemia

KN Manola - European journal of haematology, 2009 - Wiley Online Library
Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease
accounting for 15–20% of all childhood acute leukemias, while it is responsible for more …

Leukemia cells directly phagocytose blood cells in AML-associated hemophagocytic lymphohistiocytosis: a case report and review of the literature

K Hatano, T Nagai, T Matsuyama, Y Sakaguchi… - Acta …, 2014 - karger.com
Hemophagocytic lymphohistiocytosis (HLH), also called hemophagocytic syndrome (HS), is
characterized by phagocyte activation caused by uncontrolled hyperinflammation due to …

“Cannibalistic” phagocytosis in acute megakaryoblastic leukemia (AML M7) with t (10; 17)(p15; q22)

E Wang, M Stoecker - Leukemia & lymphoma, 2010 - Taylor & Francis
Phagocytic activity is occasionally observed in the malignant cells of hematopoietic
neoplasms, such as blasts in acute myeloid leukemia (AML). In the vast majority of cases of …

Two acute myeloblastic leukemia cases concomitant with hemophagocytic lymphohistiocytosis and review of the literature

A Akyay, T Celkan, G İskender, A Tükün… - Annals of Clinical & …, 2013 - Assoc Clin Scientists
We present two patients with acute myeloblastic leukemia (FAB AML-M7 and AML-M2)
complicated by hemophagocytic lymphohistiocytosis (HLH) and relevant literature review …

[PDF][PDF] 急性早幼粒细胞白血病诱导缓解后继发噬血细胞综合征1 例并文献复习

陈伟, 孔庆玲, 曹江, 齐昆明, 潘秀英… - 第十一届全国免疫学 …, 2016 - xb.xzhmu.edu.cn
目的探讨急性早幼粒细胞白血病(APL) 诱导缓解后合并噬血细胞综合征(HPS)
的诊断及治疗要点. 方法对1 例诊断APL 患者的临床特点进行分析, 并探讨其可能机制 …

Successful resolution of acute myelogenous leukemia-associated hemophagocytic lymphohistiocytosis with decitabine

S Mulay, F Bauer, A Boruchov… - Leukemia & Lymphoma, 2011 - Taylor & Francis
Hemophagocytic lymphohistiocytosis (HLH), also called hemophagocytic syndrome, is an
aggressive hyperinflammatory condition characterized by prolonged fever, cytopenias …

Cytogenetic and Cytogenomic Microarray Characterization of Chromothripsis in Chromosome 8 Affecting MOZ/NCOA2 (TIF2), FGFR1, RUNX1T1, and RUNX1 in a …

PR Koduru, K Wilson, J Wen, R Garcia… - Journal of Pediatric …, 2017 - journals.lww.com
Concurrent perturbations in different driver genes have been reported primarily in
lymphoma. In acute myeloid leukemia (AML), cases with concurrent alterations in 2 driver …

Hemophagocytosis in acute megakaryocytic leukemia: hemophagocytosis or emperipolesis?

A Akyay - Journal of Pediatric Hematology/Oncology, 2013 - journals.lww.com
To the Editor: I read with great interest the article by Wiseman et al1 regarding
hemophagocytosis by leukemic megakaryoblasts in acute megakaryoblastic leukemia. Their …

[PDF][PDF] Two Different Types of Acute Myeloid Leukemia Appeared in the Evolution of a Patient with Polycythemia Vera. The Rolls of Composite Karyotype and …

RG Mihăilă, V Bîrluțiu, A Boicean - 2018 - researchgate.net
The acute myeloid leukemia secondary to polycythemia vera has a poor prognosis and
survival. We present an extremely rare case of polycythemia vera who developed an acute …