Articular cartilage defects bring about disability and worldwide socioeconomic loss,
therefore, articular cartilage repair and regeneration is recognized as a global issue …

Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and
chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non …

The osteoarthritis (OA) symptoms cannot be fully remedied by using only a single functional
component because of its complex pathogenesis. Herein, a MnO 2 nanozyme-encapsulated …

The occurrence of osteoarthritis (OA) is highly associated with the inflammatory hypoxic
microenvironment. Yet currently no attention has been paid to fabricating hypoxia …

This paper demonstrates the hybridization of copolymer microgel with drug-loaded metal–
organic frameworks nanoparticles that can achieve excellent aqueous lubricating …

Oxidation modulators regarding antioxidants and reactive oxygen species (ROS) inducers
have been used for the treatment of many diseases. However, a systematic review that …

Selective exhaustion of over-expressed reactive oxygen species (ROS) is of great
significance in the therapy of osteoarthritis (OA) because of the inhibiting effect on oxidative …

Osteoarthritis (OA) is a degenerative joint disease and is the main cause of chronic pain and
functional disability in adults. Articular cartilage is a hydrated soft tissue that is composed of …

Oxidative stress is an important, but elusive, therapeutic target for osteoarthritis (OA).
Antioxidant strategies that target oxidative stress through the elimination of reactive oxygen …

Nanoliposomes have a broad range of applications in the treatment of autoimmune
inflammatory diseases because of their ability to considerably enhance drug transport. For …