The role of gut microbiota and leaky gut in the pathogenesis of food allergy

R Poto, W Fusco, E Rinninella, M Cintoni, F Kaitsas… - Nutrients, 2023 - mdpi.com
Food allergy (FA) is a growing public health concern, with an increasing prevalence in
Western countries. Increasing evidence suggests that the balance of human gut microbiota …

Therapeutic synthetic and natural materials for immunoengineering

A Slezak, K Chang, S Hossainy, A Mansurov… - Chemical Society …, 2024 - pubs.rsc.org
Immunoengineering is a rapidly evolving field that has been driving innovations in
manipulating immune system for new treatment tools and methods. The need for materials …

The therapeutic potential of immunoengineering for systemic autoimmunity

DA McBride, RM Jones, N Bottini… - Nature Reviews …, 2024 - nature.com
Disease-modifying drugs have transformed the treatment options for many systemic
autoimmune diseases. However, an evolving understanding of disease mechanisms, which …

In vitro assessment of the effect of four polysaccharides on intestinal bacteria of mice with colitis

S Zhang, Y Sun, Q Nie, J Hu, W Su, Z Guo… - Food …, 2023 - Wiley Online Library
Polysaccharides are typically resistant to digestion in the gastrointestinal tract and are
instead degraded by gut microbiota in the colon. As such, they are commonly employed as …

Engineering strategies to modulate the gut microbiome and immune system

K Han, J Xu, F Xie, J Crowther… - The Journal of Immunology, 2024 - journals.aai.org
The gut microbiota, predominantly residing in the colon, is a complex ecosystem with a
pivotal role in the host immune system. Dysbiosis of the gut microbiota has been associated …

[HTML][HTML] Low expression of the intestinal metabolite butyric acid and the corresponding memory pattern regulate HDAC4 to promote apoptosis in rat hippocampal …

Y Xu, S Wei, L Zhu, C Huang, T Yang, S Wang… - Ecotoxicology and …, 2023 - Elsevier
After intensive research on the gut-brain axis, intestinal dysbiosis is considered to be one of
the important pathways of cognitive decline. Microbiota transplantation has long been …

[HTML][HTML] Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food

AM Kemter, RT Patry, J Arnold, LA Hesser, E Campbell… - Cell reports, 2023 - cell.com
The increasing prevalence of food allergies has been linked to reduced commensal
microbial diversity. In this article, we describe two features of allergy-protective Clostridia …

Construction of nanoparticles from blueberry anthocyanins-lecithin/gum Arabic improves lipid droplet accumulation and gut microbiota disturbance in HFD-induced …

Z Cheng, W Wei, Y Chen, A Xu, Y Wang, B Li - International Journal of …, 2024 - Elsevier
The digestive instability of anthocyanins (ACNs) limits their application in food nutrition,
especially precision nutrition. Blueberry ACNs-loaded nanoparticles (Lipo/GA-ACNs NPs) …

Next-Generation Vaccine Development with Nanomaterials: Recent Advances, Possibilities, and Challenges

S Shetty, PC Alvarado, D Pettie… - Annual Review of …, 2024 - annualreviews.org
Nanomaterials are becoming important tools for vaccine development owing to their tunable
and adaptable nature. Unique properties of nanomaterials afford opportunities to modulate …

Strategies for the development of metalloimmunotherapies

X Sun, X Zhou, X Shi, OA Abed, X An, YL Lei… - Nature Biomedical …, 2024 - nature.com
Metal ions play crucial roles in the regulation of immune pathways. In fact, metallodrugs
have a long record of accomplishment as effective treatments for a wide range of diseases …